1-(2,3-Xylyl)piperazine monohydrochloride CAS: 80836-96-0
| Inombolo Yekhathalogi | XD93322 |
| Igama Lomkhiqizo | I-1-(2,3-Xylyl)i-piperazine monohydrochloride |
| I-CAS | 80836-96-0 |
| Ifomu le-Molecularla | I-C12H19ClN2 |
| Isisindo samangqamuzana | 226.75 |
| Imininingwane Yesitoreji | I-ambient |
Ukucaciswa Komkhiqizo
| Ukubukeka | Impushana emhlophe |
| U-Asay | 99% iminithi |
I-1-(2,3-Xylyl) i-piperazine monohydrochloride, eyaziwa nangokuthi i-2,3-dimethoxyphenylpiperazine hydrochloride, iyinhlanganisela yamakhemikhali enezinhlelo zokusebenza ezihlukahlukene ocwaningweni lwezemithi nasekuthuthukisweni.Le nhlanganisela isetshenziswa ngokuyinhloko njengendawo emaphakathi ekwakhiweni kwama-molecule ahlukahlukene e-bioactive.Okunye ukusetshenziswa okukhulu kwe-1-(2,3-Xylyl)piperazine monohydrochloride indima yayo ekwakhiweni kwama-molecule aqondise ohlelweni lwezinzwa olumaphakathi.Ngokuhlanganisa i-2,3-dimethoxyphenylpiperazine moiety kuma-molecule ezidakamizwa, abacwaningi bangashintsha isakhiwo sabo samakhemikhali, bathuthukise izakhiwo zabo zemithi futhi bathuthukise ukuhambisana kwabo nokukhetha kwama-receptors athile.Ngaphezu kwalokho, i-1-(2,3-Xylyl) i-piperazine monohydrochloride itholakele. ukuba nobudlelwane be-neuronal receptors ehlukahlukene, kufaka phakathi i-serotonin ne-dopamine receptors.Lesi sakhiwo sivuse intshisekelo ekusetshenzisweni kwayo okungaba yithuluzi lokufunda nokuqonda ukuphazamiseka okuhlukahlukene kwemizwa nezimo zengqondo.Ngokuphenya ukusebenzisana kwale nhlanganisela nama-receptors, abacwaningi bangathola ukuqonda okubalulekile ezindleleni eziyisisekelo zalezi zimo, ezingasiza ekwakhiweni kokungenelela kokwelapha okunoveli.Ucwaningo luphinde lwabonisa ukuthi i-1-(2,3-Xylyl)piperazine monohydrochloride ibonisa umsebenzi we-antimicrobial ngokumelene namagciwane athile kanye nesikhunta.Leli khono liye laholela ekuhloleni kwayo njengesandulela esingase sibe khona ekuthuthukisweni kwama-antimicrobial agents.Ngokulungisa ukwakheka kwayo noma ukuyifaka kwamanye ama-molecule, abacwaningi bangakwazi ukudala izidakamizwa ezinamandla kakhulu futhi eziphumelelayo zokwelashwa kwezifo ezibangelwa amagciwane.Kubalulekile ukuqaphela ukuthi i-1-(2,3-Xylyl) piperazine monohydrochloride kufanele iphathwe ngokuqapha futhi ngokuhambisana nemithetho efanele yokuphepha.Ulwazi lwamaphepha edatha yokuphepha kanye nokusetshenziswa kwezinto ezifanele zokuvikela kubalulekile ukuze kuqinisekiswe ukuphathwa okuphephile kanye nokunciphisa noma yiziphi izingozi ezingaba khona ezihlobene nale nhlanganisela.Kafushane, i-1-(2,3-Xylyl)piperazine monohydrochloride iyinhlanganisela eguquguqukayo enezinhlelo zokusebenza ezibalulekile ucwaningo lwezemithi.Ukusetshenziswa kwayo njengendawo ephakathi ekuhlanganiseni izidakamizwa kuvumela ukuthuthukiswa kwama-molecule anezinhlelo zokusebenza zokwelapha ezingase zibe khona ohlelweni lwezinzwa oluphakathi.Ukwengeza, ukuhlobana kwayo nama-neuronal receptors kanye nezakhiwo ze-antimicrobial kuyenza ibe ithuluzi elibalulekile ekutadisheni ukuphazamiseka kwemizwa nezifo ezithathelwanayo.Kodwa-ke, kufanele kuqashelwe lapho kusetshenzwa nale nhlanganisela ukuze kuqinisekiswe ukuphepha futhi kuncishiswe izingozi ezingaba khona.
