1-(4-Fluorophenyl)piperazine dihydrochloride CAS: 64090-19-3
| Inombolo Yekhathalogi | XD93330 |
| Igama Lomkhiqizo | I-1-(4-Fluorophenyl) i-piperazine dihydrochloride |
| I-CAS | 64090-19-3 |
| Ifomu le-Molecularla | I-C10H15Cl2FN2 |
| Isisindo samangqamuzana | 253.14 |
| Imininingwane Yesitoreji | I-ambient |
Ukucaciswa Komkhiqizo
| Ukubukeka | Impushana emhlophe |
| U-Asay | 99% iminithi |
I-1-(4-Fluorophenyl) i-piperazine dihydrochloride, eyaziwa nangokuthi i-4-FPP, iyinhlanganisela yamakhemikhali ethola ukusetshenziswa okuhlukahlukene emikhakheni yezemithi neyocwaningo.Isakhiwo sayo samangqamuzana esiyingqayizivele esiqukethe i-athomu ye-fluorine kanye nendandatho ye-piperazine kuyenza ibe yigugu ngezinjongo ezihlukahlukene, kusukela ekuthuthukisweni kwezidakamizwa kuya ekuphenyweni kwesayensi. izidakamizwa eziningana zokwelapha.Ngenxa yekhono layo lokushintsha amakhemikhali, ivumela ukudalwa kwezidakamizwa ezintsha ezinokusebenza kwekhemisi okungenzeka.Ukuba khona kwe-piperazine moiety esakhiweni sayo kunenzuzo ikakhulukazi ekuthuthukisweni kwemithi eqondise isimiso sezinzwa esimaphakathi, njengama-antipsychotics, ama-antidepressants, nama-anti-anxiety agents. Ngaphezu kwalokho, i-1-(4-Fluorophenyl) i-piperazine dihydrochloride ivame ukusetshenziswa ucwaningo lwesayensi ukuze kuphenywe izinqubo ezihlukahlukene zezinto eziphilayo.Njenge-molecule yethuluzi elisebenziseka ngezindlela eziningi, isetshenziselwa ukutadisha ukubophezela kwama-receptors, ukusebenzisana kwe-neurochemical, kanye nemiphumela yezidakamizwa ezinhlelweni ezithile emzimbeni.Abacwaningi basebenzisa le nhlanganisela ukuze baveze izindlela zokusebenza zemithi ehlukene, bacacise izinhlobo ezincane zama-receptor, futhi bahlole izindlela zokudlulisa isignali.Ngokuthola ukuqonda okujulile kwalezi zinqubo, ososayensi bangaqhubekisela phambili ulwazi oluzungeze izinkinga eziningi zemizwa nengqondo, bavule indlela yokuthuthukiswa kwamasu okwelapha anoveli.Ngaphezu kwalokho, i-1-(4-Fluorophenyl)piperazine dihydrochloride isetshenziswa njengesandulela esibalulekile Ukuhlanganiswa kwe-radioligands ye-positron emission tomography (PET).Ama-Radioligand asekelwe kule nhlanganisela, ebhalwe ngama-isotopes anemisebe, avumela ukubonwa okungahlaseli kanye nokulinganisa izinqubo ezithile ze-biochemical emzimbeni womuntu.Izindlela ezinjalo zokucabanga zinikeza ukuqonda okubalulekile ekusabalaliseni kwesamukeli, ukuhlala, kanye nokuminyana, okusiza ekuhloleni izimo ezihlukahlukene zemizwa kanye nokusiza ekuthuthukisweni kwezindlela zokwelapha ezihlosiwe.Kubalulekile ukuphatha i-1-(4-Fluorophenyl)piperazine dihydrochloride ngokuqapha, njengoba kuthathwa njengento engaba yingozi.Izinyathelo ezifanele zokuphepha kanye nezinto zokuzivikela kufanele zisetshenziswe ukunciphisa ubungozi bokuchayeka ngengozi noma ukuphathwa kabi.Kafushane, i-1-(4-Fluorophenyl)piperazine dihydrochloride iyinhlanganisela eguquguqukayo esetshenziswa emikhakheni yezemithi nocwaningo.Ukusetshenziswa kwayo kuhlanganisa ukuhlanganiswa kwezidakamizwa, ucwaningo lwezinqubo zebhayoloji, kanye nokuthuthukiswa kwama-radioligands we-PET imaging.Ulwazi lwezakhiwo zenkomponi kanye nokuphathwa ngokucophelela kubalulekile ukuze kuqinisekiswe ukuphepha nokwenza lula amagalelo ayo abalulekile ekuthuthukisweni kwesayensi nemithi.
