Imikhiqizo

(1S)-4,5-Dimethoxy-1-[(methylamino)methyl]benzocyclobutane hydrochloride inhlanganisela yamakhemikhali ebonisa izici ezithakazelisayo futhi inikeza izinhlelo zokusebenza ezingase zibe khona kumakhemikhali okwelapha nokuthuthukiswa kwezidakamizwa.Le nhlanganisela ingeyesigaba sama-phenethylamines afakwe esikhundleni futhi anazo. i-benzocyclobutane core structure.Lezi zici zesakhiwo zikwenza kube ikhandidethi elithakazelisayo ekuthuthukisweni kwemithi emisha eqondise izinqubo ezihlukahlukene zebhayoloji.Okunye okungaba khona ukusetshenziswa kwe-(1S) -4,5-Dimethoxy-1--[(methylamino)methyl]benzocyclobutane hydrochloride kuhlobene nama-receptors athile. esimisweni sezinzwa esimaphakathi.Ngokulungisa ukwakheka kwayo, abacwaningi bangakha okuphuma kokunye okubonisa ukubopha okukhethekile kuma-subtypes athile ama-receptor.Lokhu kuvula amathuba okutholwa kwezindlela zokwelapha ezintsha ezimweni ezinjengokucindezeleka, ukukhathazeka, kanye nokulutheka.Amandla e-compound njenge-serotonin receptor agonist noma umphikisi ahlolisisiwe, okuphakamisa ukusetshenziswa kwawo okungenzeka ekwelapheni ukuphazamiseka kwemizwa nezinye izimo zengqondo ezihlobene. Ngaphezu kwalokho, (1S) -4,5-Dimethoxy-1-[(methylamino)methyl] I-benzocyclobutane hydrochloride kanye nokuphuma kwayo kubonise isithembiso emkhakheni wocwaningo lokulutha izidakamizwa.Ngokusebenzelana nezinhlelo ezithile ze-neurotransmitter ebuchosheni, le nhlanganisela ingase isetshenziselwe ukulungisa izindlela zomvuzo ezihambisana nokulutheka kanye nosizo ekuthuthukisweni kwezindlela zokwelapha ezinoveli ezinkingeni zokusebenzisa kabi izidakamizwa. ku-neuroscience.Isakhiwo sayo esiyingqayizivele siyivumela ukuthi ihlanganyele nama-neuronal receptors futhi iguqule ukukhululwa kwe-neurotransmitter kanye nokuthatha.Abacwaningi bangasebenzisa i-(1S) -4,5-Dimethoxy-1--[(methylamino)methyl]benzocyclobutane hydrochloride ukuze baphenye izindlela zokubonisa izimpawu ze-neural futhi bathole imininingwane yezinqubo ezingaphansi kwezifo zezinzwa ezifana nesifo se-Alzheimer's kanye ne-Parkinson.Ngaphezu kwalokho, (1S) -4,5-Dimethoxy-1-[(methylamino)methyl]benzocyclobutane hydrochloride ibalulekile ekutholakaleni kwezidakamizwa nasekuthuthukisweni.Ubunkimbinkimbi bayo buyenza ibe isiqalo esithakazelisayo sokuhlanganiswa kwamabhizinisi amasha amakhemikhali anezinhlelo zokwelapha ezingase zibe khona.Ngokulungisa ukwakheka kwayo nokuhlola okuphuma kokunye okuhlukile, ososayensi bangahlola ukusebenzisana kwenhlanganisela nezinto ezihlosiwe ezihlukahlukene zezinto eziphilayo futhi bathole imithi emisha ebonisa ukusebenza kahle okuthuthukisiwe kanye nemiphumela engemihle eyehlisiwe.Esiphetha, (1S) -4,5-Dimethoxy-1-[( I-methylamino)methyl]benzocyclobutane hydrochloride inikeza uchungechunge lwezinhlelo zokusebenza ezingase zibe khona kukhemikhali yezokwelapha kanye ne-neuroscience.Isakhiwo sayo samakhemikhali esiyingqayizivele kanye nokuhlobana kwama-receptors athile kuyenza ibe yikhandidethi elithembisayo lokuthuthukiswa kwezindlela zokwelapha ezintsha ezindaweni zokuphazamiseka kwengqondo, ukuluthwa izidakamizwa, kanye nezifo zemizwa.Ucwaningo olwengeziwe nokuhlolwa kwale nhlanganisela kanye nokuphuma kwayo kunamandla amakhulu okuthuthukisa ukuqonda kwethu lezi zimo nokuthola izindlela zokwelapha ezintsha zokuthuthukisa impilo yabantu.