2-[(2R)-2-hydroxy-3-{[4-(3-oxomorpholin-4-yl)phenyl]amino}propyl]-1H-isoindole-1,3(2H)-dione CAS: 446292-07 -5
Inombolo Yekhathalogi | XD93407 |
Igama Lomkhiqizo | 2-[(2R)-2-hydroxy-3-{[4-(3-oxomorpholin-4-yl)phenyl]amino}propyl]-1H-isoindole-1,3(2H)-dione |
I-CAS | 446292-07-5 |
Ifomu le-Molecularla | I-C21H21N3O5 |
Isisindo samangqamuzana | 395.41 |
Imininingwane Yesitoreji | I-ambient |
Ukucaciswa Komkhiqizo
Ukubukeka | Impushana emhlophe |
U-Asay | 99% iminithi |
Inhlanganisela 2-[(2R)-2-hydroxy-3-{[4-(3-oxomorpholin-4-yl)phenyl]amino}propyl]-1H-isoindole-1,3(2H)-dione iyinkimbinkimbi i-organic molecule engase isetshenziswe emkhakheni wemithi kanye namakhemikhali emithi.Ukuba khona kwe-isoindole core kubonisa ukuthi le nhlanganisela inezici ezithile zesakhiwo ezifanele ngokwebhayoloji futhi ezitholwe kuma-molecule e-bioactive.Okuphuma ku-Isoindole kubikwe ukuthi kubonisa imisebenzi eminingi yemithi, okuhlanganisa ukulwa nokuvuvukala, i-antitumor, ne-antimicrobial properties.I-2-hydroxy-3-{[4-(3-oxomorpholin-4-yl)phenyl]amino}propyl iqembu kule nhlanganisela liqukethe iqembu le-hydroxyl (OH) elixhunywe ochungechungeni lwekhabhoni emithathu, elakha umgogodla walesi siqephu.Futhi iqukethe iqembu le-phenyl elifakwe esikhundleni se-morpholinone moiety.I-Morpholines isetshenziswe kakhulu kukhemikhali yezokwelapha ngenxa yekhono layo lokusebenzelana nezinhloso ezihlukahlukene zezinto eziphilayo futhi iye yafakwa emithini eminingi enemisebenzi ehlukahlukene.Ukuba khona kweqembu le-carbonyl (C=O) elixhunywe kumgogodla we-isoindole kuphakamisa ukuthi le nhlanganisela ingase babe namandla okusebenza njenge-ligand noma i-modulator yezinhloso ezithile zamangqamuzana ngaphakathi komzimba.Izinhlanganisela ezisekelwe ku-carbonyl ziye zasetshenziswa ekutholakaleni kwezidakamizwa ukuze zihlanganyele nama-enzyme, ama-receptors, noma amaprotheni abandakanyeka ezinqubweni zezifo ezihlukahlukene. Kodwa-ke, ngaphandle kolwazi oluthe xaxa mayelana nomsebenzi webhayoloji yale nhlanganisela noma okuhlosiwe okuqondile, kuyinselele ukunikeza incazelo ebanzi yayo. ukusetshenziswa okungenzeka.Ucwaningo olwengeziwe nokuhlola kuyodingeka ukuze kutholwe izici zayo ezinembile zesayensi yezokwelapha.Ekuphetheni, inhlanganisela engu-2-[(2R)-2-hydroxy-3-{[4-(3-oxomorpholin-4-yl)phenyl]amino}propyl ]-1H-isoindole-1,3(2H)-dione, nenhloko yayo ye-isoindole namaqembu asebenzayo, inezinhlelo zokusebenza ezingase zibe khona emkhakheni wemithi kanye namakhemikhali emithi.Ukusetshenziswa kwayo okuqondile kanye nendlela yokwenza kuyodingeka kubhekwe kabanzi ngocwaningo nokuhlola.