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2-(3,5-Dimethyl-4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-5,7-dimethoxyquinazolin-4(3H)-one Cas:1044871-04-6 Isithombe Esifakiwe
  • 2-(3,5-Dimethyl-4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-5,7-dimethoxyquinazolin-4(3H)-one Cas:1044871-04-6

2-(3,5-Dimethyl-4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-5,7-dimethoxyquinazolin-4(3H)-one Cas:1044871-04-6

Incazelo emfushane:

Inombolo Yekhathalogi: XD90961
I-Cas: 1044871-04-6
I-Molecular Formula: I-C24H29N3O4
Isisindo se-Molecular: 423.5
Ukutholakala: Kukhona kusitoki
Inani:  
I-Prepack:  
Iphakethe lenqwaba: Cela i-Quote

 


Imininingwane Yomkhiqizo

Omaka bomkhiqizo

Inombolo Yekhathalogi XD90961
Igama Lomkhiqizo 2-(3,5-Dimethyl-4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-5,7-dimethoxyquinazolin-4(3H)-one

I-CAS

 1044871-04-6

I-Molecular Formula

 I-C24H29N3O4

Isisindo samangqamuzana

 423.5
Imininingwane Yesitoreji  
Ikhodi Yentela Evumelanisiwe  

 

Ukucaciswa Komkhiqizo

Ukubukeka  
Isivivinyo  
Buwoyela iphuzu 612.6±65.0 °C(Kubikezelwe)
Ukuminyana 1.25±0.1 g/cm3(Kubikezelwe)
I-acidity coefficient (pKa)9.54±0.20(Kubikezelwe)

 

I-RVX-297 iyi-BET inhibitor enamandla kakhulu, esebenza ngomlomo ekhethelwa i-BD2.Ama-IC50 e-RVX-297 ye-BRD2(BD2), BRD3(BD2), kanye ne-BRD4(BD2) ayengu-0.08, 0.05, kanye no-0.02 μM, ngokulandelana.I-RVX-297 ivimbela ukubonakaliswa kwezakhi zofuzo ezihlukahlukene zokuvuvukala kwamangqamuzana omzimba.Ukusebenza kwe-RVX-297 kumamodeli we-preclinical wokuvuvukala okunamandla kanye ne-autoimmunity.

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    2-(3,5-Dimethyl-4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-5,7-dimethoxyquinazolin-4(3H)-one Cas:1044871-04-6

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