Imikhiqizo

I-2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl) phenol, eyaziwa nangokuthi i-TMDBP, iyinhlanganisela eyingqayizivele ethola izinhlelo zokusebenza emikhakheni ehlukahlukene, kuhlanganise ne-organic synthesis kanye nesayensi yezinto zokwakha.Isakhiwo sayo samakhemikhali siqukethe i-boron-containing cyclic ether exhunywe eqenjini le-phenolic.Okunye ukusetshenziswa okubalulekile kwe-2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl) phenol ku-organic synthesis, ikakhulukazi ku-transition-metal-catalyzed cross-coupling reactions.I-TMDBP isebenza njenge-boronic acid surrogate ngenxa yokuba khona kwe-athomu ye-boron esakhiweni sayo.Ingenza izibopho ezihlangene nezinhlobo ze-nucleophilic, njengama-organometallic reagents noma i-aryl lithium compounds, ngokusebenzisa i-athomu ye-boron, okuvumela ukwakhiwa kwebhondi ye-carbon-carbon.Lesi sakhiwo senza i-TMDBP ibe yisakhiwo esibalulekile ekuhlanganisweni kwama-molecule ezinto eziphilayo eziyinkimbinkimbi, okuhlanganisa imithi, amakhemikhali ezolimo, nezinto zokusebenza.I-TMDBP iwusizo ngokukhethekile ekuhlanganiseni izinhlanganisela zemithi.Isakhiwo sayo esiyingqayizivele sivumela ukufakwa kwama-athomu e-boron kuma-molecule ezidakamizwa, okuhlinzeka ngokubamba ukuze kulungiswe okwengeziwe noma kuthuthukiswe umsebenzi wawo webhayoloji.Ukwengeza, i-TMDBP inika amandla ukwethulwa kwezinhlelo ezinuka kamnandi ezishoda nge-electron ezakhiweni zezidakamizwa, ezingaba nomthelela ekukhetheni kwazo okuhlosiwe namandla.I-compound isetshenziswe ekuthuthukiseni ama-anti-cancer agents, ama-antibiotics, namanye ama-ejenti okwelapha.Ngaphezu kwalokho, i-2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl) phenol isetshenziswa kusayensi yezinto.I-athomu yayo ye-boron ingakha izakhiwo zokuxhumanisa nezisekelo ze-Lewis, ivule amathuba okuhlanganiswa kwezinto ezisebenzayo ezinezakhiwo ezihlukile.I-TMDBP isetshenziswe ekwenzeni izinto ezikhanyayo, amakristalu awuketshezi, nama-polymers.Lezi zinto ezisetshenziswayo zingabonisa izici ezifana nokuzwa optical, ukuphendula ngogesi, noma ukuhlelwa kwesakhiwo esithile, okwenza i-TMDBP ibe ithuluzi elibalulekile lokucwaninga nokuthuthukiswa kwezinto. -dioxaborolan-2-yl)phenol (TMDBP) ithola izinhlelo zokusebenza ku-organic synthesis nesayensi yezinto.Isakhiwo sayo se-boron esine-cyclic ether siyivumela ukuthi ibambe iqhaza ekuphenduleni kokuhlangana kwe-transition-metal-catalyzed cross-coupling, okuyenza ibe ithuluzi eliguquguqukayo ekwakhiweni kwamabhondi e-carbon-carbon.Embonini yezemithi, i-TMDBP isetshenziselwa ukuhlanganiswa kwama-molecule ezidakamizwa kanye nokuguqulwa kwezakhiwo zawo zebhayoloji.Ukwengeza, i-TMDBP isetshenziswa kwisayensi yezinto zokwakha ukudala izinto ezisebenzayo ezinezakhiwo ezihlukile.Ngamandla ayo okwenza kube lula ukuguqulwa kwamakhemikhali okuhlukahlukene, i-TMDBP idlala indima ebalulekile ekuthuthukisweni kwezinhlelo zokusebenza ezihlukahlukene, kusukela ekutholweni kwezidakamizwa kuya ekuklanyweni kwezinto ezibonakalayo.