Imikhiqizo

I-2-(Chloromethyl)-4-methylquinazoline iyinhlanganisela yamakhemikhali eyingxenye yomndeni we-quinazoline.I-Quinazolines iyinhlanganisela ye-organic enesakhiwo se-bicyclic esakhiwe indandatho ye-benzene ehlanganiswe nendandatho ye-pyrimidine.Le nhlanganisela ethile inamandla amakhulu okusetshenziswa ezinhlelweni ezihlukahlukene, kuhlanganise nesayensi yemithi kanye nezinto.Indawo eyodwa enkulu lapho i-2-(chloromethyl)-4-methylquinazoline ibonise khona isithembiso isekhemistri yezokwelapha.Okuphuma kokuphuma kwe-quinazoline kunezinhlobonhlobo zemisebenzi yebhayoloji, okuyenza ikhange ekutholakaleni nasekuthuthukisweni kwezidakamizwa.Baye bafundiswa amandla abo ekwelapheni izifo ezihlukahlukene, kuhlanganise nomdlavuza, ukuphazamiseka kwemizwa, kanye nezifo zenhliziyo.Ocwaningweni lomdlavuza, ama-quinazoline-based compounds abonise imiphumela ephikisana ne-proliferative kanye ne-anti-tumor.Ngokuvimbela izindlela ezithile noma amaprotheni ahlosiwe abandakanyeka ekukhuleni kwamangqamuzana omdlavuza kanye nokuphila, abonise amandla njengama-ejenti okwelapha asebenzayo.Ukuba khona kweqembu le-chloromethyl ku-2-(chloromethyl)-4-methylquinazoline kungase kuthuthukise ukusebenza kahle kwayo, njengoba ama-halogen substituents aboniswe ukuthuthukisa i-bioactivity nokukhetha kwezidakamizwa.Ku-neuropharmacology, okuphuma kwe-quinazoline kuye kwahlolisiswa amandla abo njengama-inhibitors. Ama-enzyme abandakanyeka ezifweni ze-neurodeergenerative, njenge-Alzheimer's kanye ne-Parkinson's.Lezi zinhlanganisela ziye zabonisa ikhono lokuwela umgoqo wegazi-ubuchopho, okubenza bathandeke ngokukhethekile ekuqondiseni isimiso sezinzwa esimaphakathi.Ngaphandle kwezicelo zabo zemithi, i-quinazolines iphinde yathola ukusetshenziswa kwesayensi yezinto.Ukwakheka kwawo okuyingqayizivele kwamangqamuzana, kuhlanganiswe nekhono lawo lokushintsha amakhemikhali ahlukahlukene, kuwenza abe amabhlogo wokwakha aguquguqukayo okuhlanganiswa kwezinto zokusebenza.Lezi zinto zingabonisa izici ezifana ne-fluorescence, i-electroconductivity, nokuqashelwa kwamangqamuzana, okuzenza zibe usizo ezindaweni ezifana ne-optoelectronics, sensing, kanye ne-catalysis.Ukuhlanganiswa nokuguqulwa kwe-2-(chloromethyl) -4-methylquinazoline kungenziwa ngendlela efanele ukuze kushune izakhiwo zayo ngokuqondile. izicelo.Ukusabela kwamakhemikhali okuhlukahlukene, njengokushintshanisa, ukuhlanganisa, nokuhlanganisa, kungasetshenziswa ukwethula amaqembu asebenzayo noma ukuguqula isakhiwo esiwumongo.Lokhu kuvumelana nezimo kuvumela abacwaningi ukuba baklame futhi bakhe okuphuma kokunye okunezakhiwo ezithuthukisiwe noma ukusebenza okuhlosiwe.Kafushane, i-2-(chloromethyl)-4-methylquinazoline iyinhlanganisela ebalulekile engase isetshenziswe kwezemithi nesayensi yezinto ezibonakalayo.I-bioactivity yayo, ikakhulukazi ocwaningweni lomdlavuza kanye ne-neuropharmacology, iyenza ibe ikhandidethi elithakazelisayo lokuthuthukiswa kwezidakamizwa.Ukwengeza, ukwakheka kwayo okuguquguqukayo kuyenza ibe yisakhiwo esibalulekile sezinto ezisebenzayo emikhakheni ehlukahlukene.Njengoba ucwaningo luqhubeka, uphenyo olwengeziwe luzoveza amandla agcwele kanye nokusebenza kwale khompiyutha emikhakheni ehlukene yesayensi nobuchwepheshe.