Imikhiqizo

I-2,2-difluoroacetamide, eyaziwa nangokuthi i-DFA, iyinhlanganisela yamakhemikhali enefomula ye-molecular C2H3F2NO.Kuyikristalu eqinile engenambala, engenaphunga futhi encibilika kuzincibilikisi ezipholile njengamanzi ne-methanol.I-2,2-difluoroacetamide inezinhlelo zokusebenza ezihlukahlukene emikhakheni ehlukene ngenxa yezakhiwo zayo eziyingqayizivele.Okunye ukusetshenziswa okuyinhloko kwe-2,2-difluoroacetamide kufana nesakhiwo se-organic synthesis.Ingabhekana nokusabela okuhlukahlukene kwamakhemikhali ukuze yakhe inhlobo ebanzi yezinhlanganisela.Isibonelo, ingasetshenziswa njengesandulela ekuhlanganisweni kwemithi, amakhemikhali ezolimo, namanye amakhemikhali amahle.Ngokusebenzisa ukuguqulwa okufanele kanye nokuguqulwa kweqembu elisebenzayo, i-2,2-difluoroacetamide ingafakwa kuma-molecule ayinkimbinkimbi, inikeze izakhiwo ezifunwayo kanye nokusebenza.Ama-molecule e-Fluorinated organic avame ukubonisa izici eziyingqayizivele njengokukhuphuka kwe-lipophilicity, ukuzinza okuthuthukisiwe, kanye ne-pharmacokinetics eshintshiwe.Ngokusebenzisa i-2,2-difluoroacetamide njengento yokuqala, osokhemisi bangakwazi ukwethula ama-athomu e-fluorine ezindaweni ezifunwayo ngaphakathi kwe-molecule, okuholela ekuhlanganiseni kwamanoveli anezici ezithuthukisiwe.Okunye ukusetshenziswa okuphawulekayo kwe-2,2-difluoroacetamide indima yayo njengeqembu elivikelayo ku-organic. ukuhlanganisa.Ingasetshenziselwa ukuvikela okwesikhashana amaqembu athile asebenzayo ngesikhathi sokusabela kwamakhemikhali.Ukuba khona kweqembu le-2,2-difluoroacetamide kuvikela iqembu elisebenzayo elivikelwe ekuphenduleni okungafunwa ohlangothini, okuvumela ukuguqulwa okuthile ukuthi kwenzeke ngokukhetha.Ngemuva kokuthi ukusabela okufunayo kwenzeke, iqembu le-2,2-difluoroacetamide lingasuswa kalula, libuyisele ukusebenza kwasekuqaleni.Ngaphezu kokusetshenziswa kwalo ku-organic synthesis, i-2,2-difluoroacetamide ithola izinhlelo zokusebenza emkhakheni we-chemistry yokuhlaziya.Ingasetshenziswa njenge-ejenti ephumayo ukuze kuthuthukiswe ukutholwa nokuhlaziywa kwezinhlanganisela ezihlukahlukene.Ngokusabela ngamaqembu athile asebenzayo noma izinhlanganisela zentshisekelo, njengama-amine noma ama-thiols, i-2,2-difluoroacetamide ingakwazi ukuhlonza nokulinganisa nge-gas chromatography, liquid chromatography, noma mass spectrometry. ihlanganiswe nezinhlelo zokusebenza ezahlukahlukene ku-organic synthesis kanye ne-analytical chemistry.Indima yayo njengesivikelo sokwakha ekuhlanganisweni kwemithi namakhemikhali ezolimo, ukusetshenziswa kwayo njengeqembu elivikelayo, kanye nokusetshenziswa kwayo njenge-ejenti ephumayo kugqamisa ukubaluleka kwayo emikhakheni ehlukene.Ikhono lokwethula ama-athomu e-fluorine kuma-molecule ngokusebenzisa i-2,2-difluoroacetamide linikeza ukufinyelela ezinhlobonhlobo zezinhlanganisela ezine-fluorinated ezinezici eziyingqayizivele.Sekukonke, ukusetshenziswa kwe-2,2-difluoroacetamide kunomthelela ekwakhiweni kwezinto ezintsha nezinhlanganisela ezinezici ezithuthukisiwe nokusebenza.