Imikhiqizo

I-2,3-Difluoro-4-ethoxybenzeneboronic acid iyinhlanganisela yamakhemikhali enezinhlelo zokusebenza ezibalulekile ku-organic synthesis, ikakhulukazi kumakhemikhali emithi kanye nocwaningo lwezemithi.Kuphuma kokunye okuphuma ku-boronic acid okufaka indandatho ye-benzene esikhundleni sama-athomu amabili e-fluorine, iqembu le-ethoxy (-OCH2CH3), kanye neqembu le-boronic acid (-B(OH)2) endaweni 4.Okunye ukusetshenziswa okuyinhloko okungu-2, I-3-Difluoro-4-ethoxybenzeneboronic acid iyisivimbe sokwakha sokuhlanganiswa kwezinto eziphilayo ezisebenzayo.Iqembu le-boronic acid liyisibambo esishintshashintshashintshayo esingabamba iqhaza ekuphenduleni kwamakhemikhali okuhlukahlukene, njengokusabela okuhlanganayo kwe-Suzuki-Miyaura, okuvumela ukwethulwa kwamaqembu ahlukahlukene asebenzayo.Le nhlanganisela ingafakwa ekuhlanganiseni kwama-ejenti emithi ahlose izifo ezithile kanye nezinqubo zezinto eziphilayo.Ukuba khona kwama-athomu e-fluorine kanye neqembu le-ethoxy kungaletha ukuzinza okuthuthukisiwe kwe-metabolic, i-bioactivity, kanye nezakhiwo ze-pharmacokinetic emithini ewumphumela.Ngaphezu kwalokho, i-2,3-Difluoro-4-ethoxybenzeneboronic acid ingasetshenziswa ekuthuthukiseni ama-probes kanye nezinzwa ze-fluorescent.Iqembu le-boronic acid linobudlelwane obuyingqayizivele bama-dioli, avame ukutholakala kuma-biomolecules afana nama-saccharides nama-nucleic acid.Lesi sakhiwo sivumela inhlanganisela ukuthi ibophe ngokukhetha futhi ithole ama-molecule athile okuqondiwe, okuvumela ukuklanywa kwamathuluzi okuxilonga azwela kakhulu nakhethekile.Ukufakwa kwama-athomu e-fluorine eringini ye-benzene kungaphinda kunikeze izici ezizuzisayo ze-spectroscopic, ezifana nokwanda kokuqina kwe-fluorescence noma ama-wavelength shifts, okuthuthukisa ukunemba nokuthembeka kwama-probes.Okunye ukusetshenziswa okuphawulekayo kwe-2,3-Difluoro-4-ethoxybenzeneboronic acid lies ekusetshenzisweni kwayo okungahle kube yibhlokhi yokwakha yokuhlanganiswa kwezinto ezinezakhiwo ezithuthukisiwe.Okuphuma ku-boronic acid kuvame ukusetshenziswa ekuhlanganiseni ama-polymers asebenzayo, angasetshenziswa emikhakheni eyahlukene, okuhlanganisa isayensi yezinto zokwakha, izinhlelo zokulethwa kwezidakamizwa, nezinzwa.Inhlanganisela eyingqayizivele yokusebenza kwe-boronic acid kanye nokufaka esikhundleni se-fluorine kule nhlanganisela inikeza amathuba okulungisa izakhiwo zezinto eziwumphumela, izici ezithuthukisayo ezifana nokuncibilika, ukuzinza, kanye nokuhlotshaniswa kwezinhloso ezithile.Lapho ubamba i-2,3-Difluoro-4-ethoxybenzeneboronic acid , kubalulekile ukulandela izimiso zokuphepha ezifanele, okuhlanganisa ukugqoka izinto zokuzivikela kanye nokusebenza endaweni engenawo umoya.I-Boronic acids ingazwela emoyeni kanye nomswakama, ngakho-ke kuhle ukuwagcina futhi kuphathe ngaphansi kwezimo ezingasebenzi ukuze kugcinwe ukusebenza kabusha kwawo nokuzinza. ikakhulukazi kukhemikhali yezokwelapha, ukuthuthukiswa kwe-fluorescent probe, kanye nesayensi yezinto zokwakha.Ukusebenza kwayo kwe-boronic acid, kanye namaqembu e-fluorine kanye ne-ethoxy, kunomthelela ekusebenzisaneni kwayo ngezindlela eziningi kanye nasekusebenziseni okungase kube khona ekuklameni izinhlanganisela ezisebenza ngokwebhayoloji, amathuluzi okuxilonga, nezinto ezithuthukile.Ukucwaninga okuqhubekayo nokuhlolwa kokusebenza kabusha kwayo kanye nezakhiwo kungase kuvumbule ukusetshenziswa okwengeziwe futhi kunikeze imininingwane kuzinhlelo zokusebenza ezintsha emikhakheni eyahlukene yesayensi.