2,3,5-Triphenyl-2H-tetrazolium chloride Cas:298-96-4 98% Impushana ecwebezelayo emhlophe/ephuzi ngokuphaphathekile
Inombolo Yekhathalogi | XD90154 |
Igama Lomkhiqizo | 2,3,5-Triphenyl-2H-tetrazolium chloride |
I-CAS | 298-96-4 |
I-Molecular Formula | I-C19H15N4·Cl |
Isisindo samangqamuzana | 334.80 |
Imininingwane Yesitoreji | 2 kuya ku-8 °C |
Ikhodi Yentela Evumelanisiwe | 29339980 |
Ukucaciswa Komkhiqizo
Ukubukeka | Impushana ecwebezelayo emhlophe-emhlophe/ephuzi |
U-Asay | Okuncane.98% |
I-Melting Point | 235 - 245 Deg C |
Ukulahlekelwa Ekumisweni | <3.0% |
Okuqukethwe Amanzi | 0.5% Ubukhulu |
Izinsalela ekushiseni | Ubukhulu.0.5% |
I-Solubility ku-EtoH | Dlula |
Ukuncibilika ku-Ethanol | Icacile futhi iphelele |
Ukuze uphenye umphumela onenzuzo wenhlanganisela ye-butyrate, i-Lactobacillus casei, ne-L-carnitine kumodeli ye-rat colitis.Amagundane ahlukaniswe ngamaqembu ayisikhombisa.Amaqembu amane athole i-butyrate yomlomo, i-L-carnitine, i-Lactobacillus casei kanye nokuhlanganiswa kwama-ejenti amathathu ngezinsuku ze-10 ezilandelanayo.Amaqembu asele afaka phakathi izilawuli ezingezinhle nezihle kanye neqembu mbumbulu.I-Macroscopic, ukuhlolwa kwe-histopathological, kanye nama-biomarker afana ne-tumor necrosis factor-alpha (TNF-α) ne-interlukin-1β (IL-1β), i-myeloperoxidase (MPO), i-thiobarbituric acid reactive substances (TBARS), kanye nekhono elincishisiwe le-plasma (FRAP) ) kwanqunywa kukholoni.Ukwelashwa okuhlangene kubonise umphumela ozuzisayo obalulekile ekunciphiseni ukuqunjelwa kwe-colitis uma kuqhathaniswa nezilawuli.Izinguquko eziphelele ekunciphiseni kwe-TNF-α (114.66 ± 18.26 vs 171.78 ± 9.48 pg/mg amaprotheni, P <0.05), IL-1β (24.9 ± 1.07 vs 33.06 ± 2.16 pg/mg amaprotheni, P2 <0. ± 0.03 vs 0.49 ± 0.04 μg/mg iphrotheni, P <0.01), MPO (15.32 ± 0.4 vs 27.24 ± 3.84 U/mg amaprotheni, P <0.05), kanye nokuphakama kwe-FRAP (23.46 ± 1.3 μmo ± 7/7 vs 1.3 L. , P <0.05) isekela okuthandwayo kokwelashwa okuhlangene ngokuqhathaniswa nezilawuli.Nakuba ama-monotherapies nawo asebenza kahle ekuthuthukiseni izimpawu zokuqunjelwa, ukwelapha okuhlanganisiwe bekungcono kakhulu ekuthuthukiseni izimpawu zokucindezeleka ze-colon oxidative ezihlanganisa i-FRAP, TBARS, kanye ne-MPO. isimo somtholampilo.