Imikhiqizo

I-3-Carboxyphenylboronic acid iyinhlanganisela ye-organic engeyesigaba sama-boronic acid.Iqukethe iqembu le-phenyl elixhunywe ku-athomu ye-boron, eliphinde lithathelwe indawo yiqembu le-carboxylic acid (-COOH) endaweni ye-para.Le nhlanganisela iye yathola ukunakwa okuphawulekayo emikhakheni ehlukahlukene ngenxa yezakhiwo zayo zamakhemikhali eziyingqayizivele kanye nohlu oluhlukahlukene lwezinhlelo zokusebenza.Indawo eyodwa lapho i-3-Carboxyphenylboronic acid ithola khona ukusetshenziswa kumkhakha we-organic synthesis.Njenge-boronic acid, ingakwazi ukubhekana nokusabela kokuhlangana kwe-Suzuki-Miyaura.Lokhu kusabela kuhilela ukuhlangana kwe-organic boronic acid ne-organic halide phambi kwe-catalyst ye-palladium.Umkhiqizo owumphumela uyinhlanganisela ye-biaryl, eyisakhiwo esibalulekile sokuhlanganiswa kwemithi ehlukahlukene, amakhemikhali ezolimo, namakhemikhali amahle.Lokhu kusabela kokuhlanganisa kusetshenziswa kabanzi ekuhlanganisweni kwama-molecule ezinto eziphilayo eziyinkimbinkimbi futhi yaziwa ngezimo zayo zokusabela ezithambile nokusebenza kahle okuphezulu.Ngaphezu kwalokho, i-3-Carboxyphenylboronic acid ifundwe kabanzi ngokusetshenziswa kwayo emkhakheni wesayensi yezinto.I-Boronic acids inezinto eziyingqayizivele ezifana nekhono labo lokwakha izibopho ezihlehliswayo ze-covalent namaqembu athile asebenzayo, ikakhulukazi ama-diol nama-catechols.Lesi sakhiwo sivumela ukwethulwa kwamaqembu asebenzayo endaweni engaphezulu noma kuma-polymers, okuvumela ukuthuthukiswa kwezinto ezinezici ezihlotshisiwe.I-3-Carboxyphenylboronic acid kanye nokuphuma kwayo kufakwe kumanethiwekhi e-polymer, ama-hydrogel, nama-coatings ukuze kuzuzwe izinto ezisabelayo ezishukumisayo, i-bioconjugation, nezinhlelo zokulethwa kwezidakamizwa.Okunye ukusetshenziswa okubalulekile kwe-3-Carboxyphenylboronic acid kumkhakha wobuchwepheshe bezinzwa.Njengoba i-boronic acid, inokuhlangana okuphezulu kwama-carbohydrate noshukela.Lesi sakhiwo sisetshenziswe ekwakhiweni kwezinzwa ze-glucose zokulawula isifo sikashukela.Ngokufaka i-3-Carboxyphenylboronic acid endaweni ye-transducer, izinguquko ekubopheni kwe-boronic acid ne-glucose zingatholwa, okuholela kumasignali alinganisekayo.Le ndlela ihlinzeka ngendlela ekhethiwe, ezwelayo, nengenayo ilebula yokuzwa ushukela.Ngamafuphi, i-3-Carboxyphenylboronic acid iyinhlanganisela eguquguqukayo enezinhlelo zokusebenza ezihlukahlukene ku-organic synthesis, isayensi yezinto ezibonakalayo, nobuchwepheshe bezinzwa.Ikhono layo lokubhekana ne-Suzuki-Miyaura coupling reaction, ukusetshenziswa kwayo ekuthuthukiseni izinto ezisabelayo ezishukumisayo, kanye nokusetshenziswa kwayo ekuzweleni i-glucose kugqamisa ukubaluleka kwayo emikhakheni eyahlukene.Njengoba ososayensi beqhubeka nokuhlola izakhiwo zayo futhi bethuthukisa okuphumayo okusha, ukusetshenziswa okungaba khona kwe-3-Carboxyphenylboronic acid kulindeleke ukuthi kwande ngokuqhubekayo.