3-Fluoro-4′-propyl-biphenylboronic acidCAS: 909709-42-8
Inombolo Yekhathalogi | XD93519 |
Igama Lomkhiqizo | I-3-Fluoro-4'-propyl-biphenylboronic acid |
I-CAS | 909709-42-8 |
Ifomu le-Molecularla | I-C15H16BFO2 |
Isisindo samangqamuzana | 258.1 |
Imininingwane Yesitoreji | I-ambient |
Ukucaciswa Komkhiqizo
Ukubukeka | Impushana emhlophe |
U-Asay | 99% iminithi |
I-3-Fluoro-4'-propyl-biphenylboronic acid iyinhlanganisela yamakhemikhali engeyesigaba sama-boronic acid.Iqukethe indandatho ye-biphenyl eneqembu le-propyl elinamathiselwe ekugcineni kanye ne-athomu ye-fluorine exhunywe komunye umkhawulo, kanye neqembu le-boronic acid.Le nhlanganisela inezinhlelo zokusebenza ezimbalwa emkhakheni we-organic synthesis, chemistry medicinal, kanye nesayensi yezinto.Okunye ukusetshenziswa okuyinhloko kwe-3-Fluoro-4'-propyl-biphenylboronic acid iwukuba i-coupling reagent ku-organic synthesis.Ivamise ukusetshenziswa ku-Suzuki-Miyaura cross-coupling reactions, okuyizindlela ezinamandla zokwenza amabhondi e-carbon-carbon.Le nhlanganisela isebenza njenge-boronate ester, isabela nge-aryl noma i-vinyl halides ngaphansi kwe-catalysis ye-palladium ukuze yakhe i-biaryl noma i-styryl compounds.Ukuba khona kwe-athomu ye-fluorine kanye neqembu le-propyl esakhiweni kungaba nomthelela ekusebenzeni kabusha nokukhetha kokusabela kokuhlangana kwesiphambano, kukwenze kube ibhulokhi yokwakha eguquguqukayo yokuhlanganiswa kwama-molecule e-organic eyinkimbinkimbi. -4'-propyl-biphenylboronic acid ingasetshenziselwa ukuklama nokuhlanganiswa kwezinhlanganisela eziphilayo ezisebenzayo.Ukuba khona kweqembu le-boronic acid kuvumela ukwakheka kwezibopho ezihlehliswayo ze-covalent nama-biomolecules, njengama-enzyme noma amaprotheni ama-receptor.Lezi zinhlanganisela zaziwa ngokuthi ama-boronate-based inhibitors futhi angasetshenziswa ukukhomba ama-enzyme athile ahilelekile ezifweni ezinjengomdlavuza noma isifo sikashukela.I-athomu ye-fluorine neqembu le-propyl lingasiza futhi ekuthuthukiseni izakhiwo ze-pharmacological zalezi zinhlanganisela, ezifana namandla, ukukhetha, nokuzinza kwe-metabolic.Ukwengeza, i-3-Fluoro-4'-propyl-biphenylboronic acid inezinhlelo zokusebenza ezingase zibe khona kwisayensi yezinto zokwakha.Ama-boronic acids aziwa ngokukwazi kwawo ukusabela ngama-diols noma ama-polyols, akha amabhondi anamandla e-covalent.Le ndawo ingaxhashazwa emkhakheni wesayensi ye-polymer ukwenza izinto zokuziphilisa noma imihlangano ye-supramolecular.Ngokuhlanganisa le nhlanganisela kuma-polymers noma i-coatings, abacwaningi bangakwazi ukwethula ukusebenza kwe-boronic acid, okuvumela ukuxhumana okubuyiselekayo kanye namandla okulungisa umonakalo noma ukubuyisela izakhiwo zemishini.Ngokufingqa, i-3-Fluoro-4'-propyl-biphenylboronic acid iyinhlanganisela ehlukahlukene ngokusetshenziswa kwe-organic synthesis, amakhemikhali emithi, kanye nesayensi yezinto.I-reactivity yayo kanye namaqembu asebenzayo ayingqayizivele ahlinzeka ngamathuba okwakhiwa kwebhondi ye-carbon-carbon ekuphenduleni okuhlangene, ukuklama kanye nokuhlanganiswa kwezinhlanganisela ze-biologically asebenzayo, nokudala izinto eziguqukayo.Amaqembu e-fluorine kanye ne-propyl athuthukisa ukusebenza kabusha kwe-compound futhi abe nomthelela ezintweni zayo zemithi noma zezinto ezibonakalayo.Lezi zici zenza i-3-Fluoro-4'-propyl-biphenylboronic acid ibe ithuluzi elibalulekile kososayensi nabacwaningi ezimbonini ezihlukahlukene, okunikela ekuthuthukisweni kokutholwa kwezidakamizwa, ubunjiniyela bezinto zokwakha, neminye imikhakha ehlobene.