Imikhiqizo

I-3-Quinolinecarboxylic acid, 7-chloro-8-cyano-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-, eyaziwa nangokuthi i-levofloxacin, iyi-antibiotic ebanzi esetshenziswa kabanzi ekwelapheni. izifo ezihlukahlukene zamagciwane.Iyingxenye yeqembu le-fluoroquinolone lama-antibiotics futhi ibonisa umsebenzi onamandla we-antimicrobial ngokumelene namagciwane e-Gram-positive kanye ne-Gram-negative. I-Levofloxacin ivame ukusetshenziswa ekulawuleni izifo zemigudu yokuphefumula njenge-bronchitis ne-pneumonia, kanye nezifo ze-urinary tract, isikhumba kanye izifo zezicubu ezithambile, kanye ne-bacterial prostatitis.Indlela yayo yokusebenza ibandakanya ukuvimbela i-DNA gyrase yebhaktheriya kanye nama-enzyme e-topoisomerase IV, abalulekile ekuphindaphindeni kwe-DNA, ukulungisa, nokuhlanganisa kabusha kubhaktheriya.Ngokuphazamisa la ma-enzyme, i-levofloxacin iphazamisa ukuhlanganiswa kwe-DNA yebhaktheriya, okuholela ekufeni kwebhaktheriya.Lesi sakhiwo sinomthelela ekusebenzeni kwayo ngokumelene namagciwane ahlukahlukene, kuhlanganise nalawo amelana namanye ama-antibiotic.Ngaphezu kwalokho, i-levofloxacin ikhombisa uhhafu wempilo ende, okuvumela ukuthi kuthathwe umthamo kanye ngosuku, okuthuthukisa ukuthobela isiguli kanye nokuba lula.Ngaphezu kokusetshenziswa kwayo ekwelapheni izifo ezivamile zamagciwane, i-levofloxacin iphinde yabonisa umsebenzi wokulwa namagciwane atypical afana ne-Mycoplasma pneumoniae ne-Legionella. pneumophila.Lokhu kwenza kube yisinqumo esifanele sokwelapha amacala e-atypical pneumonia.Ngaphezu kwalokho, i-levofloxacin itholakale iphumelela ekuqedeni i-Helicobacter pylori, i-bacterium ehambisana nokuthuthukiswa kwe-gastritis nezilonda ze-peptic.Nokho, kubalulekile ukuqaphela ukuthi ukusetshenziswa kwe-levofloxacin kufanele kwenziwe ngokuqapha, kucatshangelwa ukuthi kungenzeka imiphumela emibi kanye nokuthuthukiswa kokumelana nama-antibiotic.I-Levofloxacin iye yahlotshaniswa nemiphumela emibi efana nokucanuzela kwenhliziyo, isifo sohudo, ikhanda elibuhlungu, nesiyezi.Akufanele isetshenziswe kubantu abane-hypersensitivity eyaziwayo ku-fluoroquinolones noma ezigulini ezithile njengabesifazane abakhulelwe, omama abancelisa ibele, nezingane ezingaphansi kweminyaka engu-18. Ekugcineni, i-3-Quinolinecarboxylic acid, 7-chloro-8-cyano-1 -cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-, noma i-levofloxacin, iyi-antibiotic enamandla futhi esetshenziswa kabanzi ekwelapheni izifo ezibangelwa amagciwane.Umsebenzi wayo obanzi, ukungena kahle kwezicubu, kanye nohlobo lwemithamo olulula kwenza kube inketho yokwelapha ebalulekile.Nokho, kufanele kuqashelwe ekusetshenzisweni kwayo, kucatshangelwa imiphumela engemihle engase ibe khona kanye nesidingo sokulwa nokumelana nama-antibiotic.