Imikhiqizo

I-3-tert-Butoxycarbonylphenylboronic acid, eyaziwa nangokuthi i-Boc-Ph-B(OH)₂, iyinhlanganisela yemvelo eyingxenye yesigaba sama-boronic acid.Iqukethe indandatho ye-phenyl esikhundleni seqembu le-tert-butoxycarbonyl (Boc) kanye neqembu le-boronic acid (-B(OH)₂).Le nhlanganisela inezinhlobonhlobo zezinhlelo zokusebenza ku-organic synthesis, ikakhulukazi emkhakheni we-chemistry yezokwelapha.Okunye ukusetshenziswa okuyinhloko kwe-3-tert-Butoxycarbonylphenylboronic acid iyiqembu elivikelayo ekuhlanganiseni kwezinto eziphilayo.Iqembu le-Boc lingangezwa ngokukhetha eqenjini elisebenzayo le-amine ukuze livikeleke ekuphenduleni okungafunwa ngesikhathi sokuhlanganiswa kwama-molecule ayinkimbinkimbi.Iqembu lokuvikela le-Boc lizinzile ngaphansi kwezimo ezihlukahlukene zokusabela futhi lingasuswa kalula kamuva kusetshenziswa izimo ezine-asidi ethambile, okuvumela ukuvinjelwa okukhethiwe kweqembu le-amine.Lesi sakhiwo senza i-3-tert-Butoxycarbonylphenylboronic acid i-reagent ebalulekile ekuhlanganiseni kwama-peptides, imithi, nemikhiqizo yemvelo.Ngaphezu kwalokho, i-3-tert-Butoxycarbonylphenylboronic acid ivame ukusetshenziswa ekuphenduleni kokuhlanganisa, njengokuhlanganisa i-Suzuki-Miyaura.Iqembu le-boronic acid lingabhekana nokusabela ngezinhlobo ze-organometallic, ngokuvamile i-aryl noma i-alkyl boronate, okuholela ekwakhekeni kwebhondi ye-carbon-carbon.Lokhu kusabela kusetshenziswa kabanzi ukwakha izakhiwo zamangqamuzana eziyinkimbinkimbi futhi kwethule amaqembu e-aryl noma e-alkyl ku-molecule eqondiwe.I-3-tert-Butoxycarbonylphenylboronic acid, neqembu layo elivikelayo le-Boc, ivumela ukusabela okukhethiwe kokuhlanganisa kumasayithi athile ku-molecule, okuthuthukisa ukuguquguquka kokwenziwa kanye nokusebenza kahle.Ngaphezu kwalokho, i-3-tert-Butoxycarbonylphenylboronic acid iye yaphenywa ngezinhlelo zayo zokwelapha ezingase zibe khona.I-Boronic acids, kuhlanganise nokuphuma kwe-phenylboronic acid, ibonise imisebenzi ehlukahlukene yezinto eziphilayo, njenge-anticancer, i-antiviral, ne-antifungal properties.Ikhono le-3-tert-Butoxycarbonylphenylboronic acid lokubamba iqhaza ekuphenduleni okuhlanganayo lingasetshenziselwa ukuklama nokuhlanganisa izinhlanganisela zenoveli nemisebenzi ethuthukisiwe yebhayoloji.Abacwaningi bahlole ukuhlanganiswa kokuphuma kwe-boronic acid ye-3-tert-Butoxycarbonylphenylboronic acid futhi bahlola amandla abo ekhemisi. Sekukonke, i-3-tert-Butoxycarbonylphenylboronic acid iyinhlanganisela eguquguqukayo esetshenziswa ku-organic synthesis, ikakhulukazi njengeqembu elivikelayo kanye ne-cross-coup ukusabela.Isakhiwo sayo samakhemikhali esiyingqayizivele kanye nokusebenza kabusha kuyenza ibe i-reagent ebalulekile yokuhlanganiswa kwama-molecule ayinkimbinkimbi, kuhlanganise nama-peptides kanye nemithi.Ukwengeza, ukusetshenziswa kokwelapha okungaba khona kwe-3-tert-Butoxycarbonylphenylboronic acid kanye nokuphuma kwayo kuyenza inhlanganisela ethokozisayo ukuze iqhutshwe nokuhlolwa kukhemikhali yezokwelapha.