Imikhiqizo

I-3-Tolylboronic acid, eyaziwa nangokuthi i-3-methylphenylboronic acid, iyinhlanganisela yekhemikhali ethola ukusetshenziswa okubalulekile ku-organic synthesis kanye namakhemikhali okwelapha. .Le nhlanganisela isebenza njenge-boronic acid building block, eyenza ukwakheka kwe-carbon-carbon noma i-carbon-heteroatom bond.Isibonelo, ingabamba iqhaza ekuxhumaneni kwe-Suzuki-Miyaura, lapho isabela khona nge-aryl noma i-vinyl halide ngaphansi kwe-palladium catalysis ukuze ikhiqize izinhlanganisela ze-biaryl.Ukusabela okunjalo okuhlanganayo kunokusetshenziswa okubanzi ekuhlanganiseni kwama-molecule ezinto eziphilayo eziyinkimbinkimbi, okuhlanganisa imithi, amakhemikhali ezolimo, nezinye izinhlanganisela ezibalulekile.Ukuba khona kweqembu le-methyl endaweni yesi-3 ku-3-Tolylboronic acid kunikeza izici ezithile kokuphuma kwalo.Lokhu okufakwe esikhundleni kungaba nomthelela ekusebenzeni kabusha kwekhompompi, ukukhetha, nomsebenzi webhayoloji.Ngaphezu kwalokho, ingasebenza njengeqembu elivikelayo lamanye amaqembu asebenzayo ngesikhathi sokuguqulwa kokwenziwa.Lezi zakhiwo zenza i-3-Tolylboronic acid ibe yisakhiwo esibalulekile sokwakhiwa kwezakhiwo zamangqamuzana ahlukahlukene.Ekhemistry yezokwelapha, i-3-Tolylboronic acid kanye nokuphuma kwayo kuyathakazelisa njengabantu abangase bakwazi ukusebenzisa izidakamizwa.Ukuba khona kweqembu le-methyl kungashintsha ukusebenzisana kwekhompiyutha nokuhlosiwe kwebhayoloji, kube nomthelela amandla ayo kanye nokukhetha.Ukwengeza, i-boronic acid moiety ingakha izibopho ezihlehliswayo ze-covalent nama-enzyme athile, enikeza izindlela zokwakhiwa kwama-enzyme inhibitors.Ukuguquguquka kwayo okuhlukahlukene ekuguqulweni kokwenziwa kuvumela ukuthuthukiswa kohlu olubanzi lwama-molecule afana nezidakamizwa anezindawo ezihambisanayo.Ngaphezu kwalokho, i-3-Tolylboronic acid isetshenziswa kwezinye izindawo zocwaningo, njengesayensi yezinto zokwakha kanye ne-catalysis.Ingahlanganiswa nezinto ezithuthukisiwe, kufaka phakathi ama-polymers kanye nezinhlaka zensimbi-organic, ukwethula imisebenzi ethile.Le nhlanganisela ingase futhi isebenze njenge-ligand ezinkingeni zensimbi eziguqukayo, ibe nomthelela ekusebenzeni kwayo kwe-catalytic kanye nokukhetha ekuphenduleni okuhlukahlukene, njenge-hydrogenation ne-oxidation. isayensi yezinto zokwakha, kanye ne-catalysis.Indima yayo njengesakhiwo sokwakha i-boronic acid ivumela ukwakheka kwezinhlaka zekhabhoni eziyinkimbinkimbi, okwenza kube yigugu ekuhlanganisweni kwezinhlanganisela zezinto eziphilayo.Ukwengeza, ukuba khona kweqembu le-methyl kunikeza amathuba okuhlanganisa izakhiwo zokuphuma, futhi ukusetshenziswa kwayo ezintweni zokwakha kanye ne-catalysis kuthuthukisa ukusebenza kwezinto ezithuthukisiwe futhi kunomthelela ekuguqulweni kwamakhemikhali.