Imikhiqizo

I-5,6,7,7a-Tetrahydrothieno[3,2-c]pyridine-2(4H)-one hydrochloride, eyaziwa nangokuthi i-riluzole hydrochloride, umuthi osetshenziswa ngokuyinhloko ekwelapheni i-amyotrophic lateral sclerosis (ALS), eyaziwa nangokuthi isifo sikaLou Gehrig.Kuyimithi yomlomo esebenza ngokuguqula amazinga e-glutamate, i-neurotransmitter ejabulisayo, ebuchosheni.I-Riluzole hydrochloride kucatshangwa ukuthi isebenza ngokunciphisa ukukhululwa kwe-glutamate, ukuvimbela ukutholakala kwe-glutamate, nokuvimbela ama-receptors e-glutamate.I-Glutamate kukholakala ukuthi idlala indima ekuqhubekeleni phambili kwe-ALS futhi ngokushintsha amazinga ayo, i-riluzole hydrochloride ingase ibambezele ukuwohloka kwama-motor neurons futhi ingasiza ekwandiseni isikhathi sokuphila.Ngaphandle kokusetshenziswa kwayo ku-ALS, i-riluzole hydrochloride nayo iye yaphenywa ukusetshenziswa okungenzeka kwezinye izifo zezinzwa ezifana nesifo i-Alzheimer's, i-multiple sclerosis, nokucindezeleka.Nokho, ukusebenza kwayo kulezi zimo kusacwaningwa futhi ucwaningo olwengeziwe luyadingeka.Njenganoma yimuphi umuthi, i-riluzole hydrochloride ingabangela imiphumela emibi.Imiphumela emibi evamile ihlanganisa isicanucanu, ukuhlanza, isiyezi, ubuthakathaka, nobuhlungu besisu.Imiphumela engemihle engajwayelekile kodwa emibi kakhulu ingase ihlanganise izinkinga zesibindi, ukungezwani komzimba, nezinguquko ekubalweni kwegazi.Kubalulekile ukuxoxa nganoma yiziphi izingozi nezinzuzo ezingaba khona nomsebenzi wezempilo ngaphambi kokuqala i-riluzole hydrochloride. i-hydrochloride, umuthi osetshenziselwa ukwelapha i-ALS ngokushintsha amazinga e-glutamate ebuchosheni.Nakuba isebenza kahle ekwehliseni ijubane ukuqhubeka kwe-ALS, ingase futhi ibangele imiphumela engemihle okufanele iqashelwe.Ukusetshenziswa kwayo kwezinye izimo zemizwa kusaphenywa.