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Imikhiqizo

BCIP-Toluidine)5-Bromo-4-chloro-3-indolylphosphate-p-toluidine usawoti Cas:6578-06-9 99% Impushana emhlophe ukuya kokukhanyayo okukhanyayo Isithombe Esifakiwe
  • BCIP-Toluidine)5-Bromo-4-chloro-3-indolylphosphate-p-toluidine usawoti Cas:6578-06-9 99% Impushana emhlophe ukuya ensundu ngokukhanyayo

BCIP-Toluidine)5-Bromo-4-chloro-3-indolylphosphate-p-toluidine usawoti Cas:6578-06-9 99% Impushana emhlophe ukuya ensundu ngokukhanyayo

Incazelo emfushane:

Inombolo Yekhathalogi: XD90137
I-Cas: 6578-06-9
I-Molecular Formula: C8H5BrClNO4P·C7H10N
Isisindo se-Molecular: 433.62
Ukutholakala: Kukhona kusitoki
Inani:  
I-Prepack: 5g USD20
Iphakethe lenqwaba: Cela i-Quote

 

 

 

 

 

 

 


Imininingwane Yomkhiqizo

Omaka bomkhiqizo

Inombolo Yekhathalogi XD90137
Igama Lomkhiqizo I-BCIP-Toluidine)5-Bromo-4-chloro-3-indolylphosphate-p-toluidine usawoti
I-CAS 6578-06-9
I-Molecular Formula C8H5BrClNO4P·C7H10N
Isisindo samangqamuzana 433.62
Imininingwane Yesitoreji -15 kuya ku-20 ° C
Ikhodi Yentela Evumelanisiwe 29339980

 

Ukucaciswa Komkhiqizo

Ukubukeka Impushana emhlophe/ekhanyayo
U-Asay ≥ 99%
Iphoyinti lokuncibilika 194-195 ºC
Iphuzu elibilayo 580.2°C ku-760 mmHg
Iphoyinti le-Flash 304.7°C
Ukuncibilika I-DMF: 20 mg/mL
Ukuncibilika I-soluble ku-dimethylformamide, engancibiliki emanzini.
Ukuzwela Izwela ekukhanyeni, iyazwela emoyeni, futhi iyazwela lapho kushisa

 

Umsebenzi webhayoloji: I-BCIP (usawoti we-BCIP p-toluidine; usawoti we-X-phosphate p-toluidine) i-substrate ye-chromogenic yokutholwa kwe-colorimetric yomsebenzi we-alkaline phosphatase.

Ubuthi be-Shiga (Stxs) bukhiqizwa i-enterohemorrhagic Escherichia coli (EHEC), ebangela izifo zabantu ngomphumela ovame ukufa.Imigqa yeseli ye-Vero, ethathwe kuzinso zenkawu eluhlaza yase-Afrika, imele izinga legolide lokunquma imiphumela ye-cytotoxic ye-Stxs.Naphezu kokusetshenziswa kwawo emhlabeni wonke, ulwazi mayelana nezakhiwo eziqondile ze-Stx receptor glycosphingolipids (GSLs) kanye nokuhlanganiswa kwazo kuma-lipid rafts lumpofu.Lapha sethula ukuhlaziya kwesakhiwo okuphelele kwama-Stx receptor GSL kanye nokusatshalaliswa kwawo kulwelwesi olungazweli okokuhlanza (DRM), alungiswe kusukela kumaseli e-Vero-B4 futhi asetshenziswa njengokulingana kwe-lipid raft.Sihlonze i-globotriaosylceramide (Gb3Cer) ne-globotetraosylceramide (Gb4Cer) njengezamukeli ze-GSL ze-Stx1a, Stx2a, ne-Stx2e subtypes zisebenzisa ukutholwa kwembondela ye-TLC kuhlanganiswe ne-MS.I-Stx receptor engavamile, i-globopentaosylceramide (Gb5Cer, Galβ3GalNAcβ3Glα4Galβ4Glcβ1Cer), eyaqashelwa ngokuqondile (ngaphezu kwe-Gb3Cer ne-Gb4Cer) nge-Stx2e, yayinesimo esigcwele.Ama-Lipoforms we-Stx receptor GSLs atholwe ephethe ngokuyinhloko izingxenye ze-ceramide ezakhiwe i-sphingosine (d18:1) kanye ne-C24:0/C24:1 noma i-C16:0 fatty acid.Ngaphezu kwalokho, ukwenzeka ngokubambisana nezimpawu ze-lipid raft, i-SM ne-cholesterol, kuma-DRM kuphakamise ukuhlotshaniswa kwe-GSL nama-membrane microdomain.Lolu cwaningo lunikeza isisekelo sokuqhubeka nokuhlola umthelela osebenzayo we-lipid raft-associated Stx receptors ngokulimala okubangelwa ubuthi kumaseli e-Vero-B4.

 

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    BCIP-Toluidine)5-Bromo-4-chloro-3-indolylphosphate-p-toluidine usawoti Cas:6578-06-9 99% Impushana emhlophe ukuya ensundu ngokukhanyayo

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