I-Capastat sulfate (Capreomycin sulfate) Cas: 1405-37-4
Inombolo Yekhathalogi | XD92151 |
Igama Lomkhiqizo | I-Capastat sulfate (iCapreomycin sulfate) |
I-CAS | 1405-37-4 |
Ifomu le-Molecularla | C24H42N14O8·H2O4S |
Isisindo samangqamuzana | 752.76 |
Imininingwane Yesitoreji | 2 kuya ku-8 °C |
Ikhodi Yentela Evumelanisiwe | 29419000 |
Ukucaciswa Komkhiqizo
Ukubukeka | Impushana emhlophe |
U-Asay | 99% iminithi |
Izinsimbi ezinzima | 0.003% ubuningi |
Ukuhlonza | Ihlolwe i-Sulfate |
pH | Isixazululo esingu-3% w/v: 4.5-7.5 |
I-endotoxin yebhaktheriya | 0.35 EU/mg ubuningi |
Ukulahlekelwa Ekumisweni | 10.0% ubuningi |
Izinsalela ekushiseni | 3.0% ubuningi |
Okuqukethwe | I-Capreomycin I: 90.0% min |
Ubunyumba | Ihambisana ne-USP 32 ejwayelekile |
Amandla | Ngokwesisekelo esomisiwe: 700-1050 ug/mg |
I-Capreomycin sulfate ingusawoti we-complex ye-cyclic pentopeptides ehlukanisiwe ne-Streptomyces capreolus, eyabikwa okokuqala ngo-1962. Usawoti we-sulfate uwukwakhiwa okufinyeleleka kakhulu kwe-capreomycin futhi isetshenziselwa izicelo zemithi.Inkimbinkimbi inezingxenye ezimbili ezinkulu, i-IA ne-IB, enensalela ye-exocyclic lysine, kanye nezingxenye ezimbili ezincane ze-delysinyl, i-IIA ne-IIB.I-Capreomycin iyi-antibiotic enamandla esebenza ngokumelene ne-mycobateria, kanye ne-Gram positive kanye ne-negative organisms.I-Capreomycin isebenza ngokubopha ku-23S ribosomal subunit, iphazamise ukwakheka kwamaprotheni.
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