I-Cyclosporin A CAS:59865-13-3 I-crystalline powder emhlophe 99%
Inombolo Yekhathalogi | XD90346 |
Igama Lomkhiqizo | Cyclosporin A |
I-CAS | 59865-13-3 |
I-Molecular Formula | I-C62H111N11O12 |
Isisindo samangqamuzana | 1202.61 |
Imininingwane Yesitoreji | 2 kuya ku-8 °C |
Ikhodi Yentela Evumelanisiwe | 29419000 |
Ukucaciswa Komkhiqizo
Isivivinyo | 99% |
Ukubukeka | I-crystalline powder emhlophe |
Ibanga | USP35 |
Ukungcola | Ukungcola okuphelele:0.6% ubuningi, Ukungcola Okukodwa Okukhulu: 0.2% |
Izinsimbi ezinzima | 20ppm ubuningi |
I-acetone | 10ppm |
Ukulahlekelwa Ekumisweni | 2.0% ubuningi |
Izinga Lokushisa Lokugcina | +4% |
Ukubukeka Kwesixazululo | Isixazululo njengokucaciswa ngakunye ku-EPIV |
Izinto ezincibilikayo ze-petroleum ether | 31ppm |
Izakhiwo: Impushana emhlophe noma emhlophe, ayinaphunga futhi ayinambitheki.Incibilika kalula ku-methanol, i-ethanol noma i-acetonitrile, incibilika kalula ku-ethyl acetate, inyibilika ku-acetone noma i-ether, futhi cishe ayincibiliki emanzini.Ukujikeleza okuqondile kwalo mkhiqizo kunqunywa incwadi yamakhemikhali, futhi kuhlakazwe ku-methanol ukwenza isisombululo esiqukethe i-10 mg nge-1 ml.Ukujikeleza okuqondile kungu-182° kuya ku-192°.Ukusetshenziswa: ucwaningo lwe-biochemical.Ukuvinjelwa kwezindlela zokusayina ze-T cell receptor
Lo mkhiqizo uwuhlobo olusha lwe-immunosuppressant.Kuyi-cyclic polypeptide into eyakhiwe ngama-amino acid ayishumi nanye.Icindezela i-humoral kanye ne-cell-delivered immune immune ngaphandle kokucindezela umnkantsha kanye nokunciphisa inani lamaseli amhlophe egazi.Kungavimbela ukwenqatshwa kwezicubu ezitshaliwe noma isitho se-Chemicalbook.Isetshenziswa ngokomtholampilo ukufakelwa izinso, isibindi, amaphaphu kanye nenhliziyo.Ngaphezu kwalokho, inomphumela othile wokwelapha ezifweni ze-autoimmune, kanye ne-schistosomiasis, umalaleveva, isifo sikashukela, ingculaza, njll., kanye nezakhiwo zokulwa nokuvuvukala.
Ukwelashwa kwe-leukemia, umdlavuza, ukufakelwa kwezinso, isifo sofuba, njll.