Imikhiqizo

I-D-erythro-Hexonic acid, 2,4,6-trideoxy-3,5-O-(1-methylethylidene)-6- [(5-methyl-1,3,4-thiadiazol-2-yl)sulfonyl]- , I-1,1-dimethylethyl ester, eyaziwa nangokuthi i-2,4,6-trideoxy-3-keto-L-lyxo-hexonic acid tert-butyl ester, iyinhlanganisela yamakhemikhali enesakhiwo esiyinkimbinkimbi kanye namaqembu amaningi asebenzayo.Le nhlanganisela inezinhlelo zokusebenza ezahlukahlukene emikhakheni efana nemithi, amakhemikhali ezolimo, kanye ne-organic synthesis.Embonini yezemithi, le nhlanganisela ingasetshenziswa njengendawo emaphakathi noma yokwakha ukuze kuhlanganiswe abantu abangase bakhethe izidakamizwa.Isakhiwo sayo samakhemikhali esiyingqayizivele, okuhlanganisa namaqembu e-thiadiazole kanye ne-sulfonyl, sinikeza amathuba okuthuthukiswa kwama-molecule anoveli anemisebenzi engaba khona yezokwelapha.Abacwaningi bangakwazi ukuguqula le nhlanganisela ukuze bethule ama-substituents athile noma amaqembu asebenzayo, okuhloswe ngayo ukuklama abantu abakhetha izidakamizwa ngamandla athuthukisiwe, ukukhetha, noma ukuzinza kwe-metabolic.Ukwengeza, iqembu le-tert-butyl ester lisebenza njengeqembu elivikelayo ekusebenzeni kwe-carboxylic acid ngesikhathi sokuguqulwa kokwenziwa.Lokhu kuvikela kuqinisekisa ukuthi ukusebenza kwe-asidi kuhlala kungashintshi ngesikhathi sokuphendula kwamakhemikhali okuhlukahlukene, okuvumela ukwethulwa kokunye ukuguqulwa okufunayo ngaphandle kokuthikameze i-acid moiety.Lesi sici sibaluleke kakhulu ezinqubweni zokuhlanganiswa kwezinyathelo eziningi, lapho amanye amaqembu asebenzayo angase adinge ukuthi asetshenziswe ngokuzimela.Emkhakheni wamakhemikhali ezolimo, i-D-erythro-Hexonic acid, 2,4,6-trideoxy-3,5-O- (1-methylethylidene)-6-[(5-methyl-1,3,4-thiadiazol-2-yl)sulfonyl]-, 1,1-dimethylethyl ester ingasetshenziswa njengesiqalo sokuthuthukiswa kokuvikelwa kwezitshalo. amanxusa.Isakhiwo sawo esiyingqayizivele singavumela ukwakhiwa kokuphuma okusha okunemisebenzi ethile yokulwa nezinambuzane, ukhula, noma izifo zezitshalo.Ngokuqhubeka nokuguqulwa kanye nokwenza kahle, le nhlanganisela ingaba nomthelela ekwakhiweni kwezixazululo ze-agrochemical ezisebenzayo nezinobungani nemvelo.Ku-organic synthesis, le nhlanganisela ingasetshenziswa njenge-reagent eguquguqukayo yokwakha ama-molecule ayinkimbinkimbi.Amaqembu e-thiadiazole kanye ne-sulfonyl ahlinzeka ngamathuba okuguqulwa kwamakhemikhali ahlukahlukene, okuvumela ukwethulwa kwamaqembu asebenzayo engeziwe noma ukwakhiwa kwamanye amasistimu amandandatho.Ukuguquguquka kwayo kwesakhiwo kuyenza ibe yigugu ekuhlanganisweni kwemikhiqizo yemvelo, i-intermediate yezemithi, noma ezinye izinto ezibalulekile eziphilayo.Kubalulekile ukuqaphela ukuthi izinhlelo zokusebenza ezithile nokusetshenziswa kwe-D-erythro-Hexonic acid, 2,4,6-trideoxy-3 ,5-O-(1-methylethylidene)-6-[(5-methyl-1,3,4-thiadiazol-2-yl)sulfonyl]-, 1,1-dimethylethyl ester ingase ihluke kuye ngenjongo ehlosiwe, okuhlosiwe. inhlanganisela, nezimo zokusabela.Ososayensi nosokhemisi esikhungweni sezemfundo, embonini, noma ezikhungweni zocwaningo bangahlola amandla ayo ekutholeni izidakamizwa, ukuthuthukiswa kwe-agrochemical, noma i-synthetic chemistry.Kafushane, i-D-erythro-Hexonic acid, 2,4,6-trideoxy-3,5-O- (1-methylethylidene)-6 - [(5-methyl-1,3,4-thiadiazol-2-yl)sulfonyl]-, 1,1-dimethylethyl ester iyinhlanganisela eguquguqukayo esetshenziswa emithini yemithi, agrochemicals, kanye ne-organic synthesis. .Isakhiwo sayo esiyinkimbinkimbi kanye namaqembu asebenzayo anikeza amathuba okuguqulwa kwamakhemikhali ahlukahlukene, okwenza kube usizo ekuthuthukisweni kwemithi emisha, izixazululo ze-agrochemical, noma izinhlanganisela ezibalulekile ze-organic.Ucwaningo olwengeziwe nokuhlola kungase kwembule izinhlelo zokusebenza ezengeziwe noma izinzuzo zale nhlanganisela kuyo yonke imikhakha eyahlukene yesayensi nezimboni.