Imikhiqizo

I-Hexafluoroisopropyl methyl ether (HFIPME) iyinhlanganisela ye-ether eguquguqukayo futhi ezinzile ngamakhemikhali enezinhlobonhlobo zokusetshenziswa emikhakheni eyahlukene.Ivamise ukusetshenziswa njengesinyibilikisi, i-reagent, kanye ne-ejenti evikelayo ngenxa yezakhiwo zayo ezihlukile.Okunye ukusetshenziswa okuyinhloko kwe-HFIPME njengesinyibilikisi ezimbonini zemithi namakhemikhali.Ukuncibilika kwayo okuhle kakhulu kukho kokubili izakhi eziphilayo kanye ne-inorganic kuyenza ibe inketho ekahle yokuncibilikisa izinhlobonhlobo zezinto.I-HFIPME iwusizo ikakhulukazi ekuncibilikiseni izinhlanganisela ezine-fluorinated kakhulu, ama-peptide, nama-polymer athile.Ikhono layo lokunyibilikisa lezi zinto eziyinselele lenza libe yigugu ekutholakaleni kwezidakamizwa, kumakhemikhali emithi, kanye ne-polymer synthesis.Ngaphezu kwezakhiwo zayo zokuncibilikisa, i-HFIPME ingasebenza njenge-reagent ekuphenduleni okuthile.Isibonelo, ingasetshenziswa ukukhuthaza ukusabela kokuphelelwa amanzi emzimbeni ngokususa amanzi ezixubeni zokusabela.I-HFIPME iphinde ibe namandla okwenza i-Lewis acid catalyst ethambile, isiza ukusabela okuhlukahlukene okufana ne-Friedel-Crafts acylation kanye nokusabela kokuhamba ngebhayisikili.Ukusebenza kabusha nokukhetha kwayo kuyenza isebenze ngezindlela eziningi ku-organic synthesis.Ngaphezu kwalokho, i-HFIPME yaziwa ngamandla ayo okuzinzisa izinhlanganisela ze-labile.Ingasebenza njenge-ejenti evikelayo ukuvimbela ukuwohloka noma i-oxidation yezinto ezibucayi ngesikhathi sokugcina noma izinqubo zokusabela.Lokhu kubaluleke kakhulu ekuzinziseni ama-intermediate asebenzayo, ukuvikela amaqembu asebenzayo, kanye nokugcina ubuqotho bama-molecule athambile.Izakhiwo zokuzinzisa ze-HFIPME ziyenza ibe yigugu emkhakheni wezokwelapha, amakhemikhali ezolimo, kanye nesayensi yezinto zokwakha.Okunye okuphawulekayo ukusetshenziswa kwe-HFIPME ukusetshenziswa kwayo njengesinyibilikisi esikhalayo.Ngenxa yokubilisa kwayo okuphansi (-24.7 °C), ingasetshenziswa ekuphenduleni kwezinga lokushisa eliphansi nezinqubo.Imvelo ye-HFIPME ye-cryogenic iyenza ikwazi ukusetshenziswa emikhakheni efana ne-cryobiology, i-cryo-electron microscopy, kanye nocwaningo lwe-superconductivity.Ukwengeza, i-HFIPME ibonise amandla emkhakheni wekhemikhali yokuhlaziya, ikakhulukazi ku-spectroscopy ye-nuclear magnetic resonance (NMR).Njengento encibilikayo, inenani eliphansi le-proton, i-viscosity ephansi, nezici ezinhle kakhulu zokuncibilika, okuyenza ibe inketho efanelekile yokuhlaziywa kwe-NMR.I-HFIPME ivame ukuncanyelwa ukutadisha amasampula ayinselele, okuhlanganisa ama-peptide, amaprotheni, nemikhiqizo yemvelo.Sekukonke, i-hexafluoroisopropyl methyl ether (HFIPME) iyinhlanganisela eguquguqukayo enezinhlobonhlobo zokusetshenziswa.Izici zayo ezincibilikayo, ukusebenza kabusha, imiphumela yokuzinzisa, imvelo ye-cryogenic, nokuhambisana nokuhlaziywa kwe-NMR kuyenza ibe wusizo ezinhlelweni ezihlukahlukene zesayensi nezimboni.Ukusuka ekuhlanganiseni kwemithi kuya ku-cryobiology, i-HFIPME idlala indima ebalulekile emikhakheni eminingana.