Imikhiqizo

I-Iodoanthranilicacidmethylester, eyaziwa nangokuthi i-Aminoiodobenzoic Acid Methyl Ester, iyinhlanganisela evame ukusetshenziswa ekuhlanganiseni kwezinto eziphilayo, ikakhulukazi emkhakheni wocwaningo lwezemithi kanye nentuthuko. i-athomu endaweni yesi-5, futhi ivame ukusetshenziswa njengesisekelo sokwakha ekuhlanganiseni ama-molecule ahlukahlukene ezinto eziphilayo.Ukusetshenziswa okuyinhloko kwe-Iodoanthranilicacidmethylester ukusetshenziswa kwayo njengendawo emaphakathi ekuhlanganisweni kwemithi.Isebenza njengesiqalo sokulungiselela ama-scaffold ama-molecular ahlukahlukene anomsebenzi webhayoloji.Ngokulungisa ukwakheka kwamakhemikhali e-Iodoanthranilicacidmethylester, osokhemisi bezokwelapha bangakha ama-analogue amasha nokuphuma kokunye okunezici zokwelapha ezingaba khona.Lokhu okuphuma kokunye kungase kuphinde kuhlolwe futhi kuthuthukiswe ukuze kuthuthukiswe imithi yokwelapha izifo ezithile.Ngaphezu kwalokho, i-Iodoanthranilicacidmethylester ivamise ukusetshenziselwa ukuhlanganiswa kodayi be-fluorescent namalebula asetshenziswa ekusetshenzisweni okuhlukahlukene kokuhlaziya.Amandla okunamathisela ama-fluorophores kule nhlanganisela anika amandla ukubonwa nokulandelela ama-molecule athile noma izinqubo ze-biological in vitro kanye ne-vivo.Lawa ma-fluorescent probes athola ukusetshenziswa ocwaningweni lwe-biomedical kanye nokuxilongwa.Ngaphezu kwalokho, i-Iodoanthranilicacidmethylester ingasetshenziswa ekuhlanganiseni amakhemikhali ezolimo namanye amakhemikhali akhethekile.Ukwakheka kwayo okuguquguqukayo kuyenza ibe yinto yokuqala ekhangayo ekukhiqizeni izibulala-zinambuzane zezolimo, izibulala-khula, nezibulala-sikhunta, kanye nezinye izinhlanganisela ezisebenzayo ezisetshenziswa ezimbonini ezahlukahlukene. ngokuqapha.Izinyathelo zokuphepha ezifanele kanye nezimiso kufanele zilandelwe lapho kusetshenzwa nale nhlanganisela ukuze kuqinisekiswe inhlalakahle yabacwaningi kanye nokunciphisa noma yiziphi izingozi ezingaba khona.Kafushane, i-Iodoanthranilicacidmethylester iyinhlanganisela eguquguqukayo esetshenziswa kakhulu ekuhlanganiseni izinto eziphilayo, ikakhulukazi emkhakheni wocwaningo lwezemithi, ngenxa yekhono layo lokusebenza njengesisekelo sokwakhiwa kwezidakamizwa.Izicelo zayo zisukela ekwakhiweni kwemithi ephakathi kwemithi kuya ekukhiqizweni kodayi be-fluorescent namakhemikhali akhethekile.Ukuhlolwa okuqhubekayo kwezakhiwo zayo kanye nocwaningo olwengeziwe kungaholela ekutholakaleni kwezinhlanganisela zamanoveli ngezinjongo ezehlukene zokwelapha nezimboni.