I-Magnesium Gluconate Cas: 3632-91-5
Inombolo Yekhathalogi | I-XD92002 |
Igama Lomkhiqizo | I-Magnesium Gluconate |
I-CAS | 3632-91-5 |
Ifomu le-Molecularla | I-C12H22MgO14 |
Isisindo samangqamuzana | 414.6 |
Imininingwane Yesitoreji | I-ambient |
Ikhodi Yentela Evumelanisiwe | 29181990 |
Ukucaciswa Komkhiqizo
Ukubukeka | Impushana emhlophe |
U-Asay | 99% iminithi |
Fp | 100 °C |
ukuncibilika | Incibilika ngokukhululekile emanzini, inyibilika kancane ku-ethanol (amaphesenti angama-96), incibilika kancane ku-methylene chloride. |
Ukuncibilika kwamanzi | cishe obala |
Imiphumela ye-Pharmacological
Ukuphathwa ngomlomo kwalo mkhiqizo kungakhuphula ukuhlushwa kwe-magnesium egazini futhi kulondoloze ukugxilisa kwe-intravenous magnesium sulfate blood magnesium concentration, yokwelapha ukukhulelwa kwe-hypertension syndrome.
I-Pharmacology kanye ne-toxicology
I-Magnesium gluconate ihlukanisa ibe yi-magnesium ion kanye ne-gluconic acid ku-vivo, ebandakanyeka kukho konke ukugaywa kwamandla e-vivo futhi isebenze noma ikhuthaze izinhlelo zama-enzyme ezingaphezu kuka-300.I-Magnesium ions ibandakanyeka ekuhlanganiseni i-DNA ne-RNA kanye nokwakheka kwamangqamuzana olwelwesi lwamaseli.Lo mkhiqizo unokuphumula kwemisipha okusobala, ungadambisa i-coronary artery spasm, unciphise ukukhululwa kwe-acetylcholine, ugcine ibhalansi ye-potassium ne-magnesium ion emzimbeni, ungavimbela ukuhlangana kweplatelet okubangelwa ukuntuleka kwe-magnesium nokwakheka kwe-coronary thrombosis, futhi unomsebenzi we-calcium. ukumelana kwe-junction kanye nokuzinza kwe-membrane.
i-pharmacokinetics
Umkhiqizo ukhiqizwa ukuguqulwa kwe-glucose ku-vitro, futhi indlela yawo yokumuncwa iyafana ne-glucose.Ukumuncwa kuqala phakathi nehora elingu-1 futhi kuqhubeka ngezinga elingaguquki kuze kufike emahoreni angu-8.Uma ulambile, ukumuncwa kungase kusheshe futhi kuphelele.Isici esikhulu salo mkhiqizo ukuthi ukumuncwa kwe-cation nokugaya kwe-chelation kungcono kakhulu kunezinye izinhlobo, futhi wonke amaqembu eminyaka angamuncwa kahle ngepheshana lamathumbu.I-magnesium emuncwe ikhishwa ikakhulukazi izinso.