Imikhiqizo

I-Methyl trifluoroacetate (MFA) iyinhlanganisela yamakhemikhali enefomula yamangqamuzana i-CF3COOCH3.Iwuketshezi olungenambala olusetshenziswa kakhulu ezimbonini ezihlukahlukene ngenxa yezakhiwo zayo zamakhemikhali eziyingqayizivele.Okunye okuyinhloko okusetshenziselwa i-MFA njenge-solvent in organic synthesis.I-polar kakhulu futhi inephuzu eliphansi lokubilisa, okuyenza isebenziseke ekuncibilikiseni izinhlobonhlobo zezinto eziphilayo.I-MFA ingasetshenziswa njengendlela yokusabela ekuphenduleni kwamakhemikhali okuhlukahlukene, okuhlanganisa i-esterification, i-acylation, kanye nokusabela kwe-alkylation.Amandla ayo e-solvency, kanye nokuzinza kwawo kanye nokungabi namandla, ayenza ibe yinketho eguquguqukayo ye-solvent kumakhemikhali amaningi ezinto eziphilayo.I-MFA iphinde isetshenziswe ngokujwayelekile njengento yokuqala noma i-reagent ekuphenduleni kwamakhemikhali amaningana.Esinye sezicelo zayo eziyinhloko sinjenge-ejenti ye-methylating, lapho ingadlulisela khona iqembu le-methyl kuma-substrates ahlukahlukene.Lokhu kwenza i-MFA ibe wusizo ekuhlanganisweni kwemithi, amakhemikhali ezolimo, namanye amakhemikhali amahle.Ingasetshenziswa, isibonelo, ku-methylation yama-amines, i-alcohol, ne-thiols, okuholela ekwakhiweni kwama-intermediates abalulekile noma imikhiqizo yokugcina.Ukwengeza, i-MFA ingabamba iqhaza njenge-reactant ekuphenduleni okuhlukahlukene kokwakhiwa kwebhondi ye-C-C, njengokuhlanganisa kukaMichael noma i-Knoevenagel condensation.Okunye ukusetshenziswa okubalulekile kwe-MFA kusekukhiqizweni kwezinhlanganisela ezine-fluorinated.Isebenza njengomthombo obalulekile wamaqembu e-trifluoroacetyl (-COCF3), angethulwa kuma-molecule e-organic, anikeze izici ezibalulekile ezifana nokukhuphuka kwe-lipophilicity, ukuzinza, kanye nomsebenzi webhayoloji.I-MFA ingasetshenziswa njengesandulela sokuhlanganiswa kwemithi, amakhemikhali ezolimo, kanye nama-polymers, lapho kufunwa khona ukuba khona kwama-athomu e-fluorine.Ngaphezu kwalokho, i-MFA isetshenziswa njengesakhiwo sokuhlanganiswa kwamakhemikhali akhethekile.Ingabhekana nokuguqulwa kwamakhemikhali okuhlukahlukene, njenge-hydrolysis, i-oxidation, nokunciphisa, okuholela ekwakhekeni kwamaqembu ahlukene asebenzayo.Lokhu kuguquguquka kwenza i-MFA ibe isandulela esibalulekile sokuhlanganiswa kwamakha, ama-flavour, nezinye izinhlanganisela ezikhethekile.Kafushane, i-methyl trifluoroacetate (MFA) iyinhlanganisela eguquguqukayo enezinhlelo zokusebenza eziningi ekuhlanganiseni kwe-organic kanye nokukhiqizwa kwamakhemikhali okukhethekile.Izakhiwo zayo njenge-solvent, i-reagent, kanye nomthombo wama-athomu e-fluorine ziyenza ibe ithuluzi elibalulekile kosokhemisi ezimbonini ezihlukahlukene.Ikhono le-MFA lokuncibilikisa uhla olubanzi lwenhlanganisela yezinto eziphilayo futhi libambe iqhaza ekuphenduleni okuhlukahlukene linomthelela ekusetshenzisweni kwayo okubanzi ekuhlanganiseni kwemithi, amakhemikhali ezolimo, namanye amakhemikhali amahle.