I-Niacinamide Cas: 98-92-0
| Inombolo Yekhathalogi | XD91246 |
| Igama Lomkhiqizo | I-Niacinamide |
| I-CAS | 98-92-0 |
| Ifomu le-Molecularla | I-C6H6N2O |
| Isisindo samangqamuzana | 122.12 |
| Imininingwane Yesitoreji | I-ambient |
| Ikhodi Yentela Evumelanisiwe | 29362900 |
Ukucaciswa Komkhiqizo
| Ukubukeka | Impushana emhlophe noma ecishe ibe mhlophe noma ikristalu engenambala |
| U-Asay | ≥99% |
| I-Melting Point | 128°C ~ 131°C |
| Ukuhlonza | Okuhle |
| pH | 6.0 ~ 7.5 |
| Ukulahlekelwa Ekumisweni | ≤0.5% |
| Umlotha one-sulphate | ≤0.1% |
| Ukucaca Kwesixazululo | Kucace |
| Insimbi Enzima | ≤0.003% |
| Umbala wesixazululo | ≤BY7 |
I-Niacinamide ebizwa nangokuthi i-nicotinamide, i-vitamin B3, noma i-vitamin PP, iwuhlobo lwamavithamini ancibilikayo emanzini, angamavithamini B, njenge-coenzyme Ⅰ, nicotinamide adenine dinucleotide (NAD) kanye ne-coenzyme Ⅱ (nicotinamide adenine dinucleotide phosphate, NADP) esakhiweni somzimba womuntu lezi zinhlobo ezimbili ze-coenzyme nicotinamide ingxenye ye-hydrogenation kanye nezakhiwo ze-dehydrogenation ezibuyiseleka emuva, Idlala indima yokudlulisa i-hydrogen ku-biooxidation futhi ingakhuthaza ukuphefumula kwezicubu, inqubo ye-biooxidation kanye ne-metabolism, ebaluleke kakhulu ekugcineni ubuqotho bomzimba womuntu. izicubu ezijwayelekile, ikakhulukazi isikhumba, umgudu wokugaya ukudla kanye nesimiso sezinzwa.Uma kuntuleka, ukuphefumula kanye ne-metabolism yamangqamuzana kuyathinteka futhi i-pellagra ibangelwa, ngakho-ke lo mkhiqizo usetshenziselwa ukuvimbela nokwelashwa kwe-pellagra, i-stomatitis, i-glossitis njalonjalo.
I-Niacinamide nayo ikhiqizwa ezilwaneni kusetshenziswa i-niacinamide ne-niacin ngaphansi kwezimo eziningi ze-acoustic.I-Pellagra yenzeka lapho umzimba untula i-niacin ne-nicotinamide.Ngakho bangakwazi ukuvimbela i-pellagra.Badlala indima ekusetshenzisweni kwamaprotheni noshukela, ukuthuthukisa umsoco womuntu nezilwane.Ngaphezu kwemithi, kodwa futhi nenani elikhulu lezithako zokudla nokudla.Amandla okukhiqiza emhlabeni esedlule amathani angu-30,000.E-Japan, i-niacinamide isetshenziswa kwezokwelapha ngo-40% kanye nezithasiselo zokudla ngo-50%.Izithasiselo zokudla zibalelwa ku-10%.I-Nicotinic acid kanye ne-nicotinamide awanabo ubuthi futhi ngokuvamile aqukethwe esibindini sesilwane, izinso, imvubelo kanye noshukela werayisi endaweni yemvelo.I-LD50 ye-nicotinamide yomjovo ongaphansi kwesikhumba kumagundane yayingu-1.7 g/kg.
Sebenzisa: umuthi wamavithamini, ubambe iqhaza enqubweni ye-metabolic yomzimba, esetshenziselwa ukuvimbela nokwelashwa kokuntuleka kwe-niacin njenge-pellagra.
Sebenzisa: imikhiqizo yokunakekelwa kwesikhumba ingavimbela isikhumba esimangelengele, igcine impilo yamangqamuzana esikhumba, ikhuthaze isikhumba sibe mhlophe.Kusetshenziswa ekunakekelweni kwezinwele kungakhuthaza ukujikeleza kwegazi ekhanda, izimpande zezinwele ezinempilo, kukhuthaze ukukhula kwezinwele, kuvimbele impandla.
Isicelo: Ucwaningo lwe-Biochemical;Ukwakheka komsoco we-tissue culture medium;Imithi yokwelapha i-Chemicalbook iyiqembu le-vitamin B, elisetshenziselwa ukuvimbela nokwelapha i-pellagra, i-stomatitis, i-glossia nezinye izifo.
Sebenzisa: Ngokufanayo ne-niacin.I-soluble yamanzi ingcono kune-niacin, kodwa kulula ukwenza i-complex ene-vitamin C ne-agglomerate.Umthamo wesidakamizwa ngu-30-80 mg / kg.
Inhloso: Ucwaningo lwe-Biochemical.Kwalungiswa indlela yokwenza izicubu.Imboni yezemithi.
Sebenzisa: i-amide derivative ye-vitamin B3 kanye ne-PARP inhibitors.
