Imikhiqizo

I-Vialox, noma i-Pentapeptide-3, i-peptide yokwenziwa esebenza engxenyeni ehlukile ye-neuromuscular junction.Njengomphikisi onokuncintisana kuma-nicotinic acetylcholine receptors, i-Vialox ivimbela ukungena kwe-sodium edingekayo ukuze imicu yemisipha ihlehlise futhi inkontileka.Kungakapheli umzuzu owodwa wokwelashwa, izinkontileka zemisipha zingancishiswa kuze kufike ku-71%, futhi i-58% yemisipha yemisipha isalokhu ingasebenzi amahora amabili kamuva.I-Vialox ingavimbela imibimbi ukuthi ingajuli ngenxa yokufinyela kwemisipha.Ocwaningweni olulodwa, i-Vialox isetshenziswe kabili ngosuku izinsuku ezingama-28 kuholele ekuncipheni okucishe kube ngama-50% ekujuleni kombimbi kanye nokuba mahhedla.Ingasetshenziswa ekugxilweni kuka-0.05%–0.3% ukwelapha imibimbi yobuso nokuqinisa isikhumba.