I-Platinum(IV) chloride Cas:13454-96-1 Impushana ensundu ngokubomvu
Inombolo Yekhathalogi | XD90688 |
Igama Lomkhiqizo | I-Platinum (IV) chloride |
I-CAS | 13454-96-1 |
I-Molecular Formula | I-Cl4Pt |
Isisindo samangqamuzana | 336.89 |
Imininingwane Yesitoreji | Gcina ngaphansi kuka +30°C |
Ikhodi Yentela Evumelanisiwe | 28439090 |
Ukucaciswa Komkhiqizo
Ukubukeka | I-Powder ensundu |
Isivivinyo | 99% |
Dumfutho | 4.303 |
Iphoyinti lokuncibilika | 370 ℃ |
logP | 2.75550 |
Ukwakha umthwali wezidakamizwa kanye ne-gene vector ye-PEG-PEI-Pt.I-Polyethyleneglycol (PEG) ihlanganiswe ne-polyethylenimine (PEI 600) ne-platinum tetrachloride;I-PEG-PEI-Pt complex yakhiwe nge-ethanol.Inkimbinkimbi iphawulwe nge-XRD, UV-VIS ne-FT-IR kanti ukufingqa kwe-DNA kwahlolwa nge-electrophoretic mobility shift assay.Ukusebenza kweseli kwahlaziywa ngokuhlolwa kwe-MTT kumaseli e-Hela, B16, A293 kanye ne-COS-7 futhi ukusebenza kahle kokudluliselwa kwe-in vitro kukalwa ngamaseli e-A293 nama-B16. Isakhiwo se-PEG-PEI-Pt siphawulwe nge-XRD, UV-VIS ne-FT. -IR.I-PEG-PEI-Pt complex ikwazile ukubopha i-DNA ngesilinganiso sesisindo se-N/P sika-0.4:1;inkimbinkimbi ibonise i-cytotoxicity kumaseli we-Hela nama-B16.Inkimbinkimbi ibisebenza kahle kakhulu ekudluliselweni kwegciwane kumaseli e-A293 kanye ne-B16 kune-PEI 600.Inoveli ethwala izidakamizwa kanye ne-gene vector ye-PEG-PEI-Pt yakhiwe ngempumelelo.