I-Rifampicin CAS:13292-46-1 99% I-Orange kuya kumpushana obomvu/obomvu
Inombolo Yekhathalogi | XD90358 |
Igama Lomkhiqizo | I-Rifampicin |
I-CAS | 13292-46-1 |
I-Molecular Formula | I-C43H58N4O12 |
Isisindo samangqamuzana | 822.94 |
Imininingwane Yesitoreji | -15 kuya ku-20 ° C |
Ikhodi Yentela Evumelanisiwe | 29419000 |
Ukucaciswa Komkhiqizo
pH | 4.5-6.5 |
Isivivinyo | 99% |
Ukubukeka | Impushana ewolintshi ukuya kokubomvu/okunsundu |
Ukulahlekelwa Ekumisweni | ubuningi 1.0% |
Umlotha one-sulphate | ubuningi 1.0% |
Ukuze kuphenywe futhi kuqhathaniswe ukuvezwa kwe-recA ne-recX, izingxenye zendlela ye-SOS, elandela ukwelashwa kwe-rifampicin ezinhlotsheni ezitholakala ezidakamizwa kanye ne-MDR ye-Mycobacterium tuberculosis. ukucindezeleka kwamahora angu-36 kulandelwa ukukhishwa kwe-RNA.I-recA kanye ne-recX ekukhishweni kwe-RNA kulinganiselwa kusetshenziswa i-qRT-PCR.Uhlobo lomtholampilo lwe-MDR lwenze amazinga e-recA ngokushesha (24 h) nangaphezulu (okuphindwe ka-7) e-recA uma kuqhathaniswa nohlobo olutholakala emuthini (36 h) kuphendulwa i-rifampicin. .amazinga e-recX atholakale ekhuphuka ngokukhuphuka kwamazinga we-recA;kodwa-ke, amazinga abephezulu uma kuqhathaniswa ne-recA.Izidakamizwa ezithintekayo kanye nezinhlobo ze-MDR zinezinhlobo ezahlukene zokwethulwa kokulungiswa kwe-DNA.© The Author 2014. Ishicilelwe yi-Oxford University Press egameni le-British Society for Antimicrobial Chemotherapy.