Imikhiqizo

(S)-(+)-2-Chlorophenylglycine methyl ester hydrochloride iyinhlanganisela enefomula yamakhemikhali C9H12ClNO2·HCl.Kuwusawoti owenziwe ukusabela kwe-(S)-(+)-2-Chlorophenylglycine methyl ester ene-hydrochloric acid.Lesi sithako sivame ukusetshenziswa emkhakheni wekhemistri yezemithi.Olunye lwezinhlelo eziyinhloko ze-(S)-(+)-2-Chlorophenylglycine methyl ester hydrochloride injenge-chiral building block ekuhlanganisweni kwemithi ehlukahlukene.Ama-Chiral compounds ama-molecule akhona ngezindlela ezimbili zesithombe sesibuko, ngokuvamile esibizwa ngokuthi ama-enantiomers.Izinhlanganisela ezihlanzekile ze-enantiomerically, ezifana ne-(S)-(+)-2-Chlorophenylglycine methyl ester hydrochloride, zibalulekile embonini yezemithi njengoba zingakhetha ukusebenzisana nezinto ezihlosiwe zebhayoloji, zandise amandla futhi zinciphise imiphumela emibi yezidakamizwa. ye-chlorophenylglycine moiety ku-(S)-(+)-2-Chlorophenylglycine methyl ester hydrochloride inikeza ithuba lokuhlanganiswa kohlu oluhlukahlukene lwemithi.Isibonelo, ingasetshenziswa njengesandulela ekuhlanganisweni kwezidakamizwa ezingezona ukuvuvukala (ama-NSAID), ama-antimicrobial agents, nezinye izinhlanganisela ze-bioactive.Izithako ezithize ezixhunywe kumgogodla we-chlorophenylglycine zingahlukahluka ukuze ziguqule izici zebhayoloji zamakhompiyutha avelayo.Ngaphezu kwalokho, (S) -(+) -2-Chlorophenylglycine methyl ester hydrochloride ingasebenza njengento ephakathi yokwenziwa ekulungiseleleni ama-molecule ayinkimbinkimbi.Ingasetshenziswa kuma-multistep syntheses ukwethula ubungane kubantu abahlukahlukene bezidakamizwa.Ngokuhlanganisa le nhlanganisela ku-synthesis, osokhemisi abathaka imithi bangakwazi ukulawula i-stereochemistry ye-molecule ewumphumela, bathuthukise umsebenzi wayo webhayoloji kanye nokucaciswa kwawo.Ifomu le-hydrochloride le-(S)-(+)-2-Chlorophenylglycine methyl ester lengeza ukuzinza futhi livumela ukuphatha okuthuthukisiwe. kanye nokugcinwa kwe-compound.Ukwengeza, usawoti we-hydrochloride ungathuthukisa ukuncibilika kwenhlanganisela ezixazululweni ezinamanzi, okwenza kube lula ukuphatha ukusabela okuhlukahlukene kokwenziwa.Kubalulekile ukuqaphela ukuthi ngenkathi (S) -(+) -2-Chlorophenylglycine methyl ester hydrochloride inamandla amaningana. izinhlelo zokusebenza ekuhlanganisweni kwezinhlanganisela zemithi, ukusetshenziswa kwayo okuqondile nokusebenza kahle kungahluka kuye nge-molecule eqondiwe edingekayo kanye nezimo zokusabela.I-compound kufanele iphathwe ngokucophelela, ngokuhambisana nemigomo efanele yokuphepha kanye nemihlahlandlela ngesikhathi sokuhlanganiswa nokusetshenziswa kwayo.