I-Terbinafine hydrochloride Cas: 78628-80-5
| Inombolo Yekhathalogi | XD92374 |
| Igama Lomkhiqizo | I-Terbinafine hydrochloride |
| I-CAS | 78628-80-5 |
| Ifomu le-Molecularla | I-C21H25N · I-HCl |
| Isisindo samangqamuzana | 327.89 |
| Imininingwane Yesitoreji | -15 kuya ku-20 ° C |
| Ikhodi Yentela Evumelanisiwe | 29214900 |
Ukucaciswa Komkhiqizo
| Ukubukeka | Impushana emhlophe |
| U-Asay | 99% iminithi |
| Iphoyinti lokuncibilika | 204-208°C |
| izinga lokushisa lokugcina. | 15-25°C |
| ukuncibilika | I-methanol: i-soluble50mg/mL |
I-erbinafine hydrochloride iwuhlobo lwemithi ye-dermatologist ebanzi-spectrum allyl amine antifungal.Ithuthukiswe yi-Swiss Novartis ngeminyaka yawo-1980, futhi yavela emakethe yase-UK okokuqala ngqa ngo-1991. Igunyazwe yi-FDA yase-United States ngemithi ye-OTC ngo-1996, futhi yavela emakethe yase-United States ngokufanayo. unyaka.Njengamanje, umuthi uthengiswa emazweni angaphezu kuka-90 wegama.Ingaphazamisa ngokukhethekile ukubola kwe-biological sekwephuzile kwe-fungus sterol, ivimbele ngokukhetha umsebenzi wesikhunta se-squalene ring oxidase, futhi ivimbele ukukhishwa kwe-squalene ekwakhekeni kwe-wungal cell membrane, ngaleyo ndlela ibulale noma ivimbele ukusebenza kokhunta.Ilungele ukwelapha isikhumba se-candidiasis, njenge-tinea manuum, i-tinea, i-tinea, i-ringworm yomzimba, i-tinea versicolor, futhi iwumuthi ongcono kakhulu wokwelapha i-onychomycosis.
I-Terbinafine hydrochloride yafaka iqoqo lokuqala lezwe elamenyezelwa yi-OTC ngo-2000. Lo mkhiqizo ungowezidakamizwa ezilwa nesikhunta.Inomthelela oqinile ekuthelelekeni kwefungal okungajulile, futhi ingakwazi ukwelapha izifo eziningi zesikhumba ngokusetshenziswa ngaphandle.
