I-Tiamulin fumarate Cas: 55297-96-6
Inombolo Yekhathalogi | XD92379 |
Igama Lomkhiqizo | I-Tiamulin fumarate |
I-CAS | 55297-96-6 |
Ifomu le-Molecularla | I-C32H51NO8S |
Isisindo samangqamuzana | 609.82 |
Imininingwane Yesitoreji | 2 kuya ku-8 °C |
Ikhodi Yentela Evumelanisiwe | 29419000 |
Ukucaciswa Komkhiqizo
Ukubukeka | Impushana emhlophe/ evaliwe |
U-Asay | 99% iminithi |
I-Melting Point | 143 - 149°C |
Izinsimbi ezinzima | <10ppm |
pH | 3.1 - 4.1 |
Ukulahlekelwa Ekumisweni | <0.5% |
Ukuncibilika | Incibilika emanzini, incibilika ngokukhululeka ku-ethanol engena-hydrous futhi inyibilika ku-methanol |
Ukujikeleza kwe-Optical | +24 ukuze +28 |
Izinsalela ekushiseni | <0.1% |
Ukungcola Okuphelele | <2% |
Okuqukethwe kwamanzi (KF) | ≤ 4.0% |
I-Tiamulin iyi-analogue ye-semi-synthetic ye-pleuromutilin lapho iketango laseceleni le-hydroxyacetyl lithathelwa indawo yi-diethylaminoethylthioacetyl moiety enkulu, ehlinzeka nge-hydrophobicity enkulu.I-hemi-fumarate inikeza usawoti ozinzile onokuncibilika kwamanzi okuthuthukisiwe.I-Tiamulin iyimithi elwa namagciwane enamandla futhi ekhetha kakhulu esebenza ngokumelene nohlu lwamagciwane e-Gram positive, engenakho ukumelana namakilasi akhona emithi elwa namagciwane ngenxa yendlela yawo eyingqayizivele yesenzo yokuvimbela ukwakheka kwamaprotheni ngokubophezela esizindeni V se-23S rRNA.
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