Imikhiqizo

I-2-(3-cyano-4-isobutoxyphenyl) -4-methyl-5-thiazolecarboxylate iyinhlanganisela yamakhemikhali enezinhlobonhlobo zezinhlelo zokusebenza ezingase zibe khona emikhakheni ehlukahlukene, ikakhulukazi izimboni zemithi nezolimo.Ukwakheka kwayo okuyingqayizivele kanye nezakhiwo kuyenza ibe isakhi esibalulekile socwaningo nentuthuko.Ukusetshenziswa okukodwa okubalulekile kwe-2-(3-cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate amandla ayo njengendawo emaphakathi yemithi.Le nhlanganisela iqukethe iqembu le-cyano, elaziwa ngohlu olubanzi lwemisebenzi yebhayoloji.Osokhemisi bezokwelapha bangasebenzisa le nhlanganisela njengento yokuqala ukuze bahlanganise okuphuma kokunye okunezakhiwo ezithuthukisiwe zemithi.Ngokushintsha amaqembu asebenzayo akhona ku-molecule, abacwaningi bangakwazi ukulungisa ukusebenzisana kwayo kwezinto eziphilayo, okwenza kube ikhandidethi elithembisayo lokwakhiwa kwezidakamizwa nokutholakala.Ngaphezu kwalokho, ukuba khona kwendandatho ye-thiazole kule nhlanganisela kusikisela ukuthi ingase ibe nezinto ezilwa namagciwane.Okuphuma ku-Thiazole kubonise umsebenzi othembisayo we-antimicrobial ngokumelene nezinhlobo ezihlukahlukene zebhaktheriya ne-fungal.Abacwaningi bangaphenya amandla e-antimicrobial e-2-(3-cyano-4-isobutoxyphenyl) -4-methyl-5-thiazolecarboxylate, okuvumela ukuthuthukiswa kwama-ejenti amasha okwelapha ukulwa namagciwane angazweli emishanguzweni.Ngaphezu kwemboni yezemithi, lokhu inhlanganisela ingase isetshenziswe emkhakheni wezolimo njengesibulala-zinambuzane noma isibulala-sikhunta.Izingxenye zayo ze-cyano ne-thiazole zihlotshaniswe ne-bioactivity ngokumelene nezinambuzane eziyingozi kanye nesikhunta.Ngokusebenzisa le nhlanganisela njengesiqalo, abacwaningi bangakwazi ukuthuthukisa okuphumayo ngokucaciswa okuqondisiwe okuthuthukisiwe, ukunciphisa ubuthi ezinto eziphilayo ezingahlosiwe, nokwanda kokuqina.Ngaphezu kwalokho, ukusebenza kwe-ester ku-2-(3-cyano-4-isobutoxyphenyl) -4- I-methyl-5-thiazolecarboxylate iphakamisa ukuthi ingasebenza njengesandulela sokuhlanganiswa kwezinhlanganisela ezihlukahlukene zezinto eziphilayo.Iqembu le-ester lingenza izinguquko ukuze lenze amanye amaqembu asebenzayo, landise ukuguquguquka kwenhlanganisela kanye nezicelo ezingase zibe khona.Ukwengeza, izici zesakhiwo sale kompompi zikhombisa ukuthi ingase ibonise izinto ezihehayo zamakhemikhali nezomzimba, okuyenza ibe ikhandidethi elingase libe khona ocwaningweni lwesayensi yezinto.Iphunga elimnandi nokuhlangana kwalo kungase kunikeze izici ezinhle zokusetshenziswa okungase kube khona okufana nezinto zikagesi eziphilayo noma izinzwa.Kafushane, i-2-(3-cyano-4-isobutoxyphenyl) -4-methyl-5-thiazolecarboxylate iyinhlanganisela engase isetshenziswe emithini yemithi. , ezolimo, nesayensi yezinto zokwakha.Isakhiwo sayo esiyingqayizivele kanye nezakhi zamakhemikhali eziguquguqukayo ziyenza ibe ithuluzi elibalulekile lokutholwa kwezidakamizwa nokuklanywa, ucwaningo lwama-antimicrobial, ukuthuthukiswa kwezibulala-zinambuzane, nophenyo lwesayensi yezinto.Ukucwaninga okuqhubekayo nokuhlolwa kwezakhiwo zale nhlanganisela kuzovula amandla ayo aphelele futhi kwandise ukusetshenziswa kwayo ezimbonini ezihlukahlukene.