Imikhiqizo

I-2-Hydroxyphenylboronic acid, eyaziwa nangokuthi i-o-hydroxyphenylboronic acid, iyinhlanganisela yezinto eziphilayo esetshenziswa kabanzi emikhakheni eyahlukene, okuhlanganisa i-organic synthesis, isayensi yezinto zokwakha, kanye namakhemikhali okwelapha. i-reagent ebalulekile yokwakha ibhondi ye-carbon-carbon.Ama-acids e-Boronic, afana ne-2-Hydroxyphenylboronic acid, asabela kalula ngama-nucleophile, afana notshwala noma ama-amine, ukuze akhe i-boronate esters.Lawa ma-boronate esters enza izinguquko ezilandelayo, njengokusabela kokuhlangana kwe-Suzuki-Miyaura, okuvumela ukwakhiwa kwama-molecule ezinto eziphilayo eziyinkimbinkimbi.Lokhu kusebenza kabusha okuhlukahlukene kwenza i-2-Hydroxyphenylboronic acid ibe yisakhiwo esibalulekile ekuhlanganisweni kwemithi, amakhemikhali e-agrochemicals, namakhemikhali amahle.Ngaphezu kokwakhiwa kwebhondi ye-carbon-carbon, i-2-Hydroxyphenylboronic acid ingabhekana nokusabela okuhlukahlukene ukwethula amanye amaqembu asebenzayo.Isibonelo, ingafakwa i-oxidized ukuze yakhe ama-quinone noma ama-aryl radicals, angenziwa futhi asebenze ukuze akhiqize izikafula zamakhemikhali ezihlukahlukene.Lezi zinguquko zithuthukisa ukusetshenziswa kokwenziwa kwe-2-Hydroxyphenylboronic acid futhi zinike amandla ukudalwa kwama-molecule ayinkimbinkimbi ngokwesakhiwo.Okunye ukusetshenziswa okubalulekile kwe-2-Hydroxyphenylboronic acid kusesayensi yezinto.Iqembu le-hydroxy elikhona ku-molecule livumela ukusebenzisana okuqinile kwe-hydrogen bonding, okwenza kube ibhulokhi yokwakha ewusizo yokuklama imihlangano ye-supramolecular noma izinto zokusebenza.Ikhono lokwenza amabhondi e-hydrogen lenza ukuzihlanganisa kwe-2-Hydroxyphenylboronic acid ku-nanostructures echazwe kahle noma ukuguqulwa kwendawo ukuze kudluliselwe izici ezifiselekayo, ezifana ne-hydrophilicity ethuthukisiwe noma ukuhambisana kwe-biocompatibility.Ngaphezu kwalokho, i-2-Hydroxyphenylboronic acid ithole ukunakwa kukhemikhali yezokwelapha. ngenxa yamandla ayo njengenhlanganisela ye-bioactive.I-boronic acid moiety ingahlanganyela ngokukhetha nama-dioli noma amaqembu asebenzayo azwela i-ester kokuhlosiwe kwebhayoloji, iyenze ibe yingxenye ebalulekile ekwakhiweni kwama-enzyme inhibitors noma ama-receptor ligand.Le ndlela esekelwe e-boronate ibonise isithembiso ekuthuthukisweni kwemithi yokwelapha izifo ezihlukahlukene, kuhlanganise nomdlavuza, isifo sikashukela, nokuvuvukala.Sekukonke, i-2-Hydroxyphenylboronic acid iyinhlanganisela eguquguqukayo enezinhlelo zokusebenza ezibalulekile ku-organic synthesis, isayensi yezinto zokwakha, kanye namakhemikhali emithi.Ukusebenza kabusha kwayo ekwakhekeni kwebhondi ye-carbon-carbon, ikhono lokwethula amanye amaqembu asebenzayo, kanye namandla njengengxube ye-bioactive kuyenza ithuluzi elibalulekile kubacwaningi emikhakheni eyahlukene yesayensi.