Imikhiqizo

I-compound 2,4,5-Trifluorobenzyl bromide iyinhlanganisela yemvelo enefomula yamakhemikhali ethi C7H5BrF3.Kuyinhlanganisela enamakha okuyingxenye ye-benzyl derivatives.I-compound ibonakala ngokuba khona kwama-athomu amathathu e-fluorine ahlanganiswe neqembu le-benzyl kanye ne-athomu ye-bromine.Okunye okuyinhloko kwe-2,4,5-trifluorobenzyl bromide ku-organic synthesis.Ingasetshenziswa njengendlela yokwakha eguquguqukayo ekulungiseleleni izinhlanganisela ezihlukahlukene.Iqembu le-trifluoromethyl ku-compound linikeza ukuphinda kusebenze okuyingqayizivele kanye nezakhiwo ezingasetshenziselwa ukuhlanganiswa kwama-molecule ezinto eziphilayo eziyinkimbinkimbi.Isibonelo, i-compound ivame ukusetshenziswa ekwakhiweni kwemithi ye-fluorinated pharmaceuticals, agrochemicals, kanye nezinye izinhlanganisela eziphilayo ezisebenzayo.I-reactivity ye-2,4,5-trifluorobenzyl bromide ingahlotshaniswa nokuba khona kwe-athomu ye-bromine.I-athomu ye-bromine isebenza njengeqembu elishiya futhi inika amandla ukusabela kokushintsha lapho i-bromine ithathelwa indawo amanye amaqembu asebenzayo.Lesi sakhiwo senza i-compound ibe wusizo ekuhlanganisweni kwezinhlanganisela ezihlukahlukene ngokusebenza kweqembu le-benzyl.Ukwengeza, ama-athomu e-fluorine akhipha i-electron kakhulu akhipha i-electron angaba nomthelela ekusebenzeni kabusha kanye nokuzinza kwemikhiqizo etholakala ku-2,4,5-trifluorobenzyl bromide.Ukuba khona kwama-athomu e-fluorine kungathuthukisa ukuzinza kwezidakamizwa zezidakamizwa futhi kwandise i-lipophilicity, engathinta izakhiwo zabo ze-pharmacokinetic, njengokumuncwa nokusatshalaliswa kwazo emzimbeni.2,4,5-Trifluorobenzyl bromide ingathola futhi ukusetshenziswa njenge-reagent noma phakathi ekuphenduleni kwamakhemikhali okuhlukahlukene.Isibonelo, ingabamba iqhaza ekuhlanganiseni ukusabela, okufana ne-Suzuki-Miyaura cross-coupling, ukwenza amabhondi e-carbon-carbon.Lokhu kusabela kunomsebenzi obanzi ekuhlanganiseni kwemithi kanye ne-agrochemical synthesis.Ekuphetheni, i-2,4,5-Trifluorobenzyl bromide iyinhlanganisela eguquguqukayo esetshenziswa ku-organic synthesis.Iqembu layo le-trifluoromethyl kanye ne-athomu ye-bromine inikeza amathuba okwakhiwa kwama-molecule ayinkimbinkimbi nokusebenza kweqembu le-benzyl.Ukusebenza kabusha kwenhlanganisela kanye nezakhiwo kuyenza ibe wusizo ekuhlanganisweni kwemithi, amakhemikhali e-agrochemicals, nezinye izinhlanganisela ezisebenza ngebhayoloji.Ngaphezu kwalokho, ingasebenza njenge-reagent ewusizo noma ephakathi ekuphenduleni kwamakhemikhali okuhlukahlukene.