Imikhiqizo

I-3-(Difluoromethyl) -1-methyl-1H-pyrazole-4-carboxylic acid iyinhlanganisela yamakhemikhali enezinhlelo zokusebenza ezihlukahlukene emkhakheni wezokwelapha kanye nokuhlanganiswa kwezinto eziphilayo.Le nhlanganisela ingeyesigaba se-pyrazole carboxylic acids, aziwa ngemisebenzi yawo ehlukahlukene yezinto eziphilayo kanye nokusetshenziswa okungenzeka kokwelapha.Okunye kwezicelo ezibalulekile ze-3-(Difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid njengokuthi ibhulokhi yokwakha noma okuphakathi ekuhlanganisweni kwezinhlanganisela zemithi.Ingasetshenziselwa ukwakha okuphuma kokunye nama-analogue anezakhiwo ezifiselekayo, njenge-pharmacokinetics ethuthukisiwe, ukukhetha okuthuthukisiwe, nemiphumela engemihle encishisiwe.Ngokusebenzisa ukwakheka kwamakhemikhali kwalesi sithako, osokhemisi bezokwelapha bangakwazi ukuklama futhi bahlanganise abantu abasha bezidakamizwa eziqondiswe ezifweni ezihlukahlukene neziyaluyalu. Ngaphezu kwalokho, i-3-(Difluoromethyl) -1-methyl-1H-pyrazole-4-carboxylic acid ingasetshenziswa njengesiqalo. impahla ekuhlanganisweni kwamakhemikhali e-agrochemicals aqukethe i-pyrazole.I-Pyrazoles ibonise imisebenzi yokubulala izinambuzane, yokubulala ukhula, kanye nesikhunta, okuyenza ibe wusizo ekuthuthukisweni kwamakhemikhali okuvikela izitshalo.Izingxenye ze-difluoromethyl kanye ne-carboxylic acid zingashintshwa ukuze zethule izici ezithile, kuthuthukise ukusebenza kwayo kanye nephrofayili yezemvelo. Ngaphezu kwalokho, i-3-(Difluoromethyl) -1-methyl-1H-pyrazole-4-carboxylic acid ingase isetshenziswe emkhakheni wezinto ezibonakalayo. isayensi.Isakhiwo sayo esiyingqayizivele kanye nokusebenza kabusha kungasetshenziswa ukuze kuhlanganiswe izinto zokusebenza ezinezici ezifiselekayo, njengama-polymers, ama-catalysts, nama-ligand.Lezi zinto ezisetshenziswayo zingasetshenziswa ezinhlelweni ezihlukahlukene, okuhlanganisa izinzwa, okokunamathelayo, nama-catalysts okusabela kwamakhemikhali.Imisebenzi engaba khona yebhayoloji yenhlanganisela kanye nekhono layo lokushintsha ama-receptors athile akwenza kube okuhlosiwe okukhangayo ocwaningweni lwesayensi yemithi.Ukusebenzisana kwayo namaphrotheni okuqondiwe kungaphenywa kusetshenziswa amasu afana ne-molecular docking, izifundo zobudlelwano bomsebenzi wesakhiwo, kanye nokuhlolwa kwezinto eziphilayo.Lezi zifundo zinganikeza ukuqonda okubalulekile endleleni yokusebenza kwenhlanganisela futhi kusize ekutholakaleni kwama-ejenti amasha okwelapha. embonini yezemithi, emkhakheni we-agrochemical, isayensi yezinto ezibonakalayo, kanye nocwaningo lwebhayoloji.Ukuguquguquka kwayo kokwenziwa kanye nemisebenzi yokwelapha engaba khona iyenza ibe yisakhiwo esibalulekile sokwakhiwa kwemithi emisha namakhemikhali ezolimo.Ukuhlolwa okwengeziwe kwezakhiwo zayo zebhayoloji nokusetshenziswa kwayo emikhakheni eyahlukene kungase kuholele ekutholakaleni kwezinhlanganisela zenoveli ezinezakhiwo ezizuzisayo nezindlela zokusebenza.