Imikhiqizo

(3R,4S)-1-tert-Butyl 3-ethyl 4-aminopyrrolidine-1,3-dicarboxylate hydrochloride iyinhlanganisela yamakhemikhali enezinhlelo zokusebenza ezihlukahlukene ku-organic synthesis kanye nocwaningo lwezemithi.Isakhiwo sayo samangqamuzana esiyingqayizivele, esihlanganisa indandatho ye-pyrrolidine ene-tert-butyl ne-ethyl substituents, kanye nokusebenza kwe-carboxylate, inikeza izici ezithakazelisayo nezinhlelo zokusebenza ezingase zibe khona.Okunye ukusetshenziswa okuyinhloko kwe-(3R,4S) -1-tert-Butyl 3- I-ethyl 4-aminopyrrolidine-1,3-dicarboxylate hydrochloride iyindima yayo njengebhlokhi yokwakha e-chiral ku-organic synthesis.Ukuba khona kwama-stereocenters ezikhundleni ze-3R ne-4S kunikeza ithuba lokudala ama-molecule ayinkimbinkimbi ane-stereochemistry ethile.Lesi sakhi singasebenza njengesiqalo sokuhlanganiswa kwezinhlanganisela ze-chiral ezihlukahlukene, njenge-intermediate yemithi, imikhiqizo yemvelo eyinkimbinkimbi, kanye namakhemikhali e-agrochemicals.Ukwengeza, (3R,4S) -1-tert-Butyl 3-ethyl 4-aminopyrrolidine-1, I-3-dicarboxylate hydrochloride ingasetshenziswa njenge-catalyst noma i-ligand ku-catalysis ye-asymmetric.Umgogodla wayo we-chiral pyrrolidine ungaheha ubumnandi nomsebenzi okhuthazayo ukukhuthaza ukusabela okukhethiwe.Le nhlanganisela ingasetshenziswa ekuguquleni okuhlukahlukene, okufana ne-enantioselective synthesis yama-molecule ephilayo, ama-pharmaceutical intermediates, nezinye izinhlanganisela ezibalulekile. Ngaphezu kwalokho, (3R,4S) -1-tert-Butyl 3-ethyl 4-aminopyrrolidine-1,3- I-dicarboxylate hydrochloride inezinhlelo zokusebenza ezingase zibe khona ocwaningweni lwamakhemikhali ezokwelapha.Izici zayo zesakhiwo kanye nezakhiwo ze-chiral ziyenza ibe yithuluzi elibalulekile ekuthuthukisweni kwentsha yezidakamizwa.Le nhlanganisela ingasetshenziswa ukuhlola ubudlelwano bomsebenzi wesakhiwo, ukuthuthukisa izakhiwo zemithi, kanye nokuthuthukisa umsebenzi webhayoloji noma ukukhetha okuhlosiwe kwezidakamizwa ezithile.Ngaphezu kwalokho, (3R,4S) -1-tert-Butyl 3-ethyl 4-aminopyrrolidine-1, I-3-dicarboxylate hydrochloride ingafakwa kumalabhulali wezinhlanganisela zokuhlolwa komphumela ophezulu ezinhlelweni zokutholwa kwezidakamizwa.Lemitapo yolwazi eyinhlanganisela ingahlolwa ngokuqhathanisa nezinhloso zebhayoloji ehlukahlukene ukuze kuhlonzwe izinhlanganisela ezingaba umthofu kanye namakhandidethi ezidakamizwa.Imvelo ye-chiral yale nhlanganisela ingaba nomthelela ekutholakaleni kwemithi emisha yokwelapha enezakhiwo ezithuthukisiwe zemithi.Ngokufingqa, (3R,4S) -1-tert-Butyl 3-ethyl 4-aminopyrrolidine-1,3-dicarboxylate hydrochloride isetshenziswa ngezindlela ezihlukahlukene. ihlanganiswe nezicelo ku-organic synthesis kanye nocwaningo lwezemithi.Izici zayo ze-chiral kanye neqembu elisebenzayo ziyenza ibe yisakhiwo esibalulekile sokuhlanganiswa kwama-molecule ayinkimbinkimbi kanye ne-asymmetric catalysis.Ngaphezu kwalokho, amandla ayo ocwaningweni lwamakhemikhali ezokwelapha nasezinhlelweni zokutholwa kwezidakamizwa agqamisa ukubaluleka kwawo ekuthuthukisweni kwezinhlanganisela zemithi ezinoveli.Izakhiwo eziguquguqukayo nezihlukile ze-(3R,4S)-1-tert-Butyl 3-ethyl 4-aminopyrrolidine-1,3-dicarboxylate hydrochloride ziyenza ibe yimpahla ebalulekile emkhakheni we-organic chemistry, ucwaningo lwezemithi, nokuthuthukiswa kwezidakamizwa.