Imikhiqizo

I-Tert-butyl 3-acetylpyrazolo[1,5-a]pyridin-5-ylcarbamate iyinhlanganisela yamakhemikhali eyaziwa ngokusetshenziswa kwayo okuhlukahlukene ekuhlanganiseni kwezinto eziphilayo kanye namakhemikhali emithi.Ngesakhiwo sayo samangqamuzana esiyingqayizivele, le nhlanganisela inezinto ezithokozisayo kanye nokusetshenziswa okungase kube khona emikhakheni ehlukahlukene yocwaningo.Okunye okuyisisekelo kwe-tert-butyl 3-acetylpyrazolo[1,5-a]pyridin-5-ylcarbamate ukusetshenziswa kwayo njengesakhiwo. block ku-organic synthesis.I-pyrazolo[1,5-a] scaffold ye-pyridine, ehlanganiswe ne-carbamate kanye namaqembu asebenzayo e-acetyl, inikeza ithuba lokuhlanganisa le nhlanganisela ekuhlanganiseni kwama-molecule e-organic complex.Ingasetshenziswa njengesiqalo sokwakhiwa kwezinhlanganisela ze-heterocyclic, i-pharmaceutical intermediate, noma ezinye izinto eziphilayo ezibalulekile. Ngaphezu kwalokho, i-tert-butyl 3-acetylpyrazolo[1,5-a]pyridin-5-ylcarbamate ibamba izicelo ezingase zibe khona kumakhemikhali okwelapha. kanye nokutholakala kwezidakamizwa.Ukuba khona kwe-pyrazolo[1,5-a]pyridine core kuphakamisa amandla ayo njenge-pharmacophore, isici sesakhiwo esibhekene nomsebenzi wezinto eziphilayo zomuthi.Ngokushintsha okushintshiwe kumaqembu e-carbamate noma i-acetyl, kungenzeka ukuhlola ubudlelwano bomsebenzi wesakhiwo kanye nokwandisa izakhiwo zekhemisi zekhompompi.Le nhlanganisela ingase ihlolwe ngokumelene nezinhloso ezihlukahlukene zezinto eziphilayo, njengama-enzyme noma ama-receptors, ukuze kuhlonzwe izinhlanganisela ezingaba umthofu zokuthuthukiswa kwezidakamizwa ezintsha.Ngaphezu kwalokho, i-tert-butyl 3-acetylpyrazolo[1,5-a]pyridin-5-ylcarbamate nayo isebenza njengethuluzi eliwusizo ocwaningweni lwebhayoloji yamakhemikhali, elivumela ukucwaninga kwezinqubo zebhayoloji kanye nokusebenzisana kwamangqamuzana.Isakhiwo sayo esiyingqayizivele, esihlanganiswe nethuba lokwethula omaka abafanelekile noma amaqembu asebenzayo, kungenza kube lula ukulebula nokulandelela ama-biomolecule athile, njengamaprotheni noma ama-nucleic acid, ekuhlolweni kweselula noma kwamakhemikhali ezinto eziphilayo.Le nhlanganisela ingasiza abacwaningi ukuba bacacise izindlela zezinto eziphilayo, ukusebenzisana kwamaprotheni namaprotheni, noma indlela yokusebenza yezindlela zokwelapha ezingase zibe khona.Ngaphezu kwalokho, i-tert-butyl 3-acetylpyrazolo[1,5-a]pyridin-5-ylcarbamate ingathola ukusetshenziswa kwesayensi yezinto ezibonakalayo, ikakhulukazi ekuthuthukisweni kwezinto ezisebenzayo noma odayi.Izakhiwo zayo ze-elekthronikhi neziqinile zingalungiselelwa ukufaka isandla ekwakhiweni kwezinto ezibonakalayo ezifiselekayo, zikagesi, noma zemishini.Isibonelo, ingahle ifakwe kuhlaka lwama-semiconductors ephilayo noma isetshenziswe njenge-chromophore kuma-diode akhipha ukukhanya noma amaseli elanga. Sekukonke, i-tert-butyl 3-acetylpyrazolo[1,5-a]pyridin-5-ylcarbamate iyimisebenzi eminingi ihlanganiswe nezicelo eziningi ku-organic synthesis, i-chemistry yezokwelapha, i-chemical biology, nesayensi yezinto ezibonakalayo.Isakhiwo sayo esiyingqayizivele namaqembu asebenzayo ahlinzeka ngesisekelo sokuhlanganiswa kwama-molecule ayinkimbinkimbi, ukuthuthukiswa kwezidakamizwa emisha, ukucwaninga kwezinqubo zebhayoloji, kanye nokwakhiwa kwezinto zokusebenza.Ukusetshenziswa okuhlukahlukene kwale nhlanganisela kugqamisa ukubaluleka kwayo emikhakheni eyahlukene yocwaningo kanye namandla ayo okufaka isandla ekuthuthukisweni kwesayensi nobuchwepheshe.