Imikhiqizo

I-Agmatine iwumkhiqizo we-decarboxylation ye-arginine eyenziwe yi-L-arginine decarboxylase (L-ADC).Kuyi-neurotransmitter futhi isatshalaliswa ezingxenyeni eziningi zezicubu nezicubu ezilwaneni ezincelisayo.Okuqondene nesitho esithile, njengamaseli e-adrenal chromaffin, amaseli e-glial, nama-carotid body spherocyte.Idatha yocwaningo ikhombisa ukuthi i-agmatine inemisebenzi yebhayoloji efana nokwehlisa ushukela wegazi, ukwehlisa umfutho wegazi, i-diuresis, i-anti-inflammatory, i-antidepressant, kanye nokuvimbela ukwanda kwamaseli, ikakhulukazi umphumela wayo ophikisayo kuma-N-methyl-D-aspartate receptors.Iqinile futhi ihlala njalo, futhi inomphumela wokuhoxa kwamakhemikhali ekuluthweni kwe-morphine yezilwane.Kuwuhlobo lokususa ubuthi bezidakamizwa ngenani elikhulu lokuthuthuka.Njengosawoti wokwelapha we-agmatine, i-agmatine sulfate inethuba elibanzi lokusetshenziswa kwemakethe.Futhi i-agmatine isebenza ngokugqugquzela ukukhululwa kwamahomoni ku-hypothalamus, okuhlanganisa i-hormone ye-luteinizing ne-hormone yokukhula, futhi ikhulisa amazinga e-nitric oxide ngezindlela ezimbili: ivuselela ukukhululwa kwe-nitric oxide futhi ivimbele ukuhlanganiswa kwe-nitric oxide, engakhuphula amazinga e-nitric oxide.Ithuthukisa ukubekezelelana ngokomzimba, isheshisa ukululama ngokomzimba (ngokuvamile ukululama ngemva kokuzivocavoca), ithuthukisa ukusebenza komzimba, ibonisa ukuthuthwa kwamandla okumangalisayo nokuhlala isikhathi eside, futhi ithuthukisa ukwakheka komzimba okuphelele.

I-Agmatine inemisebenzi yebhayoloji efana nokwehlisa ushukela wegazi, ukwehlisa umfutho wegazi, i-diuresis, anti-inflammatory, antidepressant, kanye nokuvimbela ukwanda kwamaseli.Inomthelela wokuhoxa ekuncikeni kwe-morphine yezilwane futhi iwuhlobo lokuqeda ubuthi ezidakamizwa ngenani elikhulu lokuthuthuka.