I-Ampicillin sodium salt CAS:69-52-3 99% Impushana emhlophe noma emhlophe
| Inombolo Yekhathalogi | XD90372 |
| Igama Lomkhiqizo | I-Ampicillin sodium usawoti |
| I-CAS | 69-52-3 |
| I-Molecular Formula | I-C16H18N3NaO4S |
| Isisindo samangqamuzana | 371.39 |
| Imininingwane Yesitoreji | 2 kuya ku-8 °C |
| Ikhodi Yentela Evumelanisiwe | 29411000 |
Ukucaciswa Komkhiqizo
| Amanzi | <0.2% |
| Izinsimbi ezinzima | <20ppm |
| Isivivinyo | 99% |
| Ukujikeleza kwe-Optical | +258° - +287° |
| N,N-dimethylaniline | <0.2% |
| Amandla | 845--988ug/mg (into engenamanzi) |
| Ukubukeka | Impushana emhlophe noma emhlophe |
Izinhlobo ze-Uropathogenic ze-Escherichia coli (UPEC) ziyimbangela enkulu yokutheleleka nge-bacterial tract urinary tract.Ukusinda emgudwini wegazi kuhlotshaniswa nezindlela ezahlukene ezisiza ukumelana nokubulawa kwe-serum complement-mediated.Nakuba i-phenotypic heterogeneity yamabhaktheriya iboniswe ukuthi inomthelela ekubekezeleleni ama-antibiotic, ukuthi kungenzeka ukuthi kwenza amaseli aphikisane nokubulawa amasosha omzimba awakahlolwa ngokuhlolwa.Kulolu cwaningo lwamanje sifuna ukunquma ukuthi ngabe ukuhlukahluka kwamasiko ebhaktheriya kuyahambisana yini nokuqondiswa kwebhaktheriya ngohlelo lokugcwalisa i-serum.Siqaphe ukuhlukana kwamaseli kuhlobo lwe-UPEC lwe-CFT073 ngephrotheni yentatheli ye-fluorescent.Amangqamuzana esigaba esimile afakwe ku-serum yomuntu esebenzayo noma engavunyelwe ukushisa lapho kukhona noma engekho ama-antibiotic ahlukene (i-ampicillin, i-norfloxacin, ne-amikacin), futhi ukuhlukaniswa kwamaseli kanye nokubopha amaprotheni okuhambisana ne-C3 kukalwa nge-flow cytometry kanye ne-immunofluorescence microscopy.I-Heterogeneity ezikhathini eziphindwe kabili zamaseli e-CFT073 ku-serum yenze ukuba abantu abancane abathathu abahlukene bahluke, bonke baqashelwa ingxenye ye-C3 yohlelo lokuhambisana.Isibalo samaseli akhula ngokushesha amelana ne-serum complement-mediated lysis.Ukugcwala okukhulu kwamaseli anezinga lokukhula elimaphakathi kusengozini yokuthola i-serum.Isibalo sabantu sesithathu, esingaqalisi ukukhula lapho sihlanjululwa esigabeni esimile, sivikelekile kanyekanye ekuhlanganisweni kwe-serum kanye nama-antibiotics.
