I-Carbenicillin Disodium Salt Cas: 4800-94-6 89-109% Impushana emhlophe ukuya emhlophe
| Inombolo Yekhathalogi | I-XD90196 |
| Igama Lomkhiqizo | Carbenicillin disodium Usawoti |
| I-CAS | 4800-94-6 |
| I-Molecular Formula | I-C17H16N2Na2O6S |
| Isisindo samangqamuzana | 422.3633 |
| Imininingwane Yesitoreji | 2 kuya ku-8 °C |
| Ikhodi Yentela Evumelanisiwe | 29411000 |
Ukucaciswa Komkhiqizo
| pH | 5.5 ~ 7.5 |
| Okuqukethwe Amanzi | ≤ 6.0% |
| Ukuncibilika | Isixazululo esicacile nesiphuzi |
| Isivivinyo | 99% |
| Amandla | 830 ug/mg |
| Ama-Pyrogens | ≤80mg/kg |
| Ukudlulisa | Iyahambisana |
| Ukubukeka | Impushana emhlophe ukuya kokumhlophe |
| Iodine Emunca Izinto | ≤8.0% |
| Ibanga le-Usp | Iyahambisana |
| I-Assay (i-penicillin G) | Iyahambisana |
Ukulimala kwesibindi okubangelwa izidakamizwa kungenye yezimbangela eziyinhloko zokuphelelwa amandla kwezidakamizwa.Ikhono lokubikezela imiphumela yesibindi yabantu abasebenzisa izidakamizwa kusuka ezinhlakeni zabo zamakhemikhali kubalulekile ukusiza ukuqondisa amaphrojekthi okuhlola okutholwa kwezidakamizwa aye emithini ephephile.Kulolu cwaningo, sihlanganise isethi yedatha yezinhlanganisela ze-951 ezibikwe ukuthi zikhiqize imiphumela eminingi esibindini ngezinhlobo ezahlukene, ezihlanganisa abantu, amagundane, nama-nonrodents.Imiphumela yesibindi yale sethi yedatha yatholwa njengemethadatha eqinisekisayo, ekhiqizwe ezifushaneni ze-MEDLINE kusetshenziswa inhlanganisela eyingqayizivele yezindlela ze-lexical nezilimi kanye nemithetho ye-ontological.Sihlaziye le sethi yedatha sisebenzisa izindlela ezivamile ze-cheminformatics futhi sabhekana nemibuzo eminingana ephathelene nokukhonkodensi kwezinhlobo ezahlukene zemiphumela yesibindi, izinqumo zamakhemikhali zemiphumela yesibindi kubantu, kanye nokubikezela ukuthi ingabe isakhi esinikezwe kungenzeka sibangele umphumela wesibindi kubantu.Sithole ukuthi i-concordance yemiphumela yesibindi yayiphansi kakhulu (ca. 39-44%) phakathi kwezinhlobo ezahlukene, okuphakamisa ukuthi kungenzeka ukuthi ukucaciswa kwezinhlobo ezithile kungase kuncike ezicini ezithile zesakhiwo samakhemikhali.Izithako zahlanganiswa ukufana kwazo kwamakhemikhali, futhi izinhlanganisela ezifanayo zahlolwa ukuze kutholwe ukufana okulindelekile kwamaphrofayili azo omphumela wesibindi esincike ezinhlobonhlobo.Ezimweni eziningi, amaphrofayili afanayo abonwa kumalungu eqoqo elifanayo, kodwa amanye amakhomponi avela njengangaphandle.Abangaphandle babeyisihloko sokuqinisekiswa okugxilwe kabusha kusuka ku-MEDLINE kanye neminye imithombo yedatha.Kwezinye izimo, ukugomela okwengeziwe kwebhayoloji kukhonjwe, okwakuhambisana nokulindela okusekelwe ekufananeni kwamakhemikhali enhlanganisela.Ukugomela kuphinde kwaguqulelwa ezichasiselweni kanambambili zamakhemikhali ayisisekelo (okungukuthi, umphumela wesibindi uma uqhathaniswa nomphumela wesibindi), futhi amamodeli we-binary quantitative quantitative-activity relationship (QSAR) akhiqizwa ukuze abikezele ukuthi ingabe inhlanganisela ingalindeleka ukuthi ikhiqize imiphumela yesibindi kubantu.Naphezu kokungafani okubonakalayo kwedatha, amamodeli abonise amandla amahle okubikezela ahlolwe izinqubo zokuqinisekisa okuphambene okuphindwe izikhathi ezi-5.Amandla angaphandle okubikezela amamodeli we-QSAR kanambambili aphinde aqinisekiswa ngokusetshenziswa kwawo kumakhompiyutha abuyiselwe noma afundwa ngemuva kokwakhiwa kwemodeli.Ngokwazi kwethu konke, lolu wucwaningo lokuqala lokubikezela ubuthi bamakhemikhali olwasebenzisa ukumodela kwe-QSAR kanye namanye amasu e-cheminformatics kudatha yokubona ekhiqizwa ngezindlela zokumba umbhalo okuzenzakalelayo ngokucushwa okulinganiselwe okwenziwa ngesandla, okuvula amathuba amasha okukhiqiza nokumodela ubuthi bamakhemikhali. idatha.
