I-Colistin Sulfate Cas: 1264-72-8
Inombolo Yekhathalogi | XD92222 |
Igama Lomkhiqizo | I-Colistin Sulfate |
I-CAS | 1264-72-8 |
Ifomu le-Molecularla | I-C52H98N16O13 |
Isisindo samangqamuzana | 1155.43 |
Imininingwane Yesitoreji | 2 kuya ku-8 °C |
Ikhodi Yentela Evumelanisiwe | 29419000 |
Ukucaciswa Komkhiqizo
Ukubukeka | Impushana emhlophe iye cishe emhlophe |
U-Asay | 99% iminithi |
pH | 4-6 |
Ukulahlekelwa Ekumisweni | <3.5% |
Ukuncibilika | Incibilika ngokukhululeka emanzini, incibilika kancane ku-ethanol (96%), cishe ayincibiliki ku-acetone trichloromethane noma i-diethyl ether |
I-sulfate | 16 - 18% |
Ukujikeleza okuqondile okubonakalayo | -63 kuya ku-73 |
Ukungcola Okuphelele | <23% |
Umlotha one-sulfate | <1% |
Amandla (isisekelo esomisiwe) | >19000u/mg |
1.Kuyi-antibiotic eyisisekelo ye-peptide, ikakhulukazi yokuvimbela nokwelashwa kwezifo ezithathelwanayo futhi ikhuthaze ukukhula kwezilwane.
2.Ingahlanganiswa ne-cell membrane i-lipoprotein phosphate mahhala, okwenza ukungezwani kwe-membrane yeseli kunciphe, kukhuphuke ukungena, okuholela ekuphumeni kwe-cytoplasm yokufa kweseli.
3.Inomphumela onamandla ovimbelayo ngokumelene namagciwane angenayo igram (ikakhulukazi i-E. coli, i-Salmonella, i-Pseudomonas aeruginosa, i-Proteus ne-Haemophilus, njll.), ayinawo umthelela kumagciwane e-Gram-positive (Staphylococcus aureus futhi ngaphandle kwe-hemolytic streptococcus ngaphandle) isikhunta.
4. I-Colistin sulfate oral ilukhuni ukumunca, incane ubuthi, kulula ukubangela izinsalela zezidakamizwa, kulula ukukhiqiza ukumelana nezidakamizwa.