I-Cytochrome C CAS:9007-43-6 Impushana ebomvu noma emnyama emnyama
| Inombolo Yekhathalogi | XD90330 |
| Igama Lomkhiqizo | I-Cytochrome C |
| I-CAS | 9007-43-6 |
| I-Molecular Formula | I-C42H54FeN8O6S2 |
| Isisindo samangqamuzana | 886.91 |
| Imininingwane Yesitoreji | -15 kuya ku-20 ° C |
| Ikhodi Yentela Evumelanisiwe | 35040090 |
Ukucaciswa Komkhiqizo
| Ukubukeka | Impushana ebomvu noma emnyama |
| Isivivinyo | 99% |
| pH | 5-7 |
| Insimbi | 0.40 - 0.48% |
| Ubumsulwa | Ubuncane 90% |
| Izinsalela ekushiseni | Ubukhulu 1.5% |
| Umswakama | Ubukhulu obungu-6% |
| Ubunyumba | Ihambisana nokuhlolwa kobunyumba |
| Ama-Pyrogens | Mahhala |
| Ukuhlolwa kombala | Okuhle |
| E. Coli | Akekho |
| Izinhlobo ze-Salmonella | Akekho |
| I-Solubility 10% emanzini | Kucace ngombala obomvu |
| Inani lokuqothula | Er/Eo:Min1.1 |
| Isamba se-Microbial Count cfu / g | Ubukhulu be-100 |
| Isikhunta/Imvubelo | Akekho |
| Umsuka | Inhliziyo yehhashi |
Izincwadi ezisafufusa zisikisela ukuthi i-bisphenol A (BPA), ikhemikhali ephazamisa ukusebenza kwe-endocrine esabalele, lapho ukuchayeka kwenzeka esemncane, ingase yandise ingozi ye-metabolic syndrome.Kulolu cwaningo, siphenye i-hypothesis yokuthi ukuchayeka kwe-perinatal ku-BPA kubeka inzalo engozini yesifo sesibindi esinamafutha: ukubonakaliswa kwesibindi kwe-metabolic syndrome, kanye nendlela okungenzeka ngayo.Amagundane e-Wistar akhulelwe anikezwa i-BPA (40μg/kg/ngosuku) noma imoto ngesikhathi sokukhulelwa nokuncelisa.I-histology yesibindi, ukuhlaziywa kwamakhemikhali ezinto eziphilayo, i-transcriptome, kanye nomsebenzi we-mitochondrial kwahlolwa enzalweni yesilisa ngemva kokubeletha 3, 15 kanye namaviki angu-26.Emavikini angu-3 ubudala, i-morphology engavamile yesibindi kanye nokusebenza akuzange kubonwe enzalweni evezwe yi-BPA, kodwa ukwehla komsebenzi we-mitochondrial breathing complex (MRC) (I no-III) kanye nezinguquko eziphawulekayo ekubonakalisweni kwezakhi zofuzo ezihilelekile ku-mitochondrial fatty acid metabolism. kubhekwe uma kuqhathaniswa nezilawuli.Emavikini ayi-15, i-micro-vesicular steatosis esibindini, izakhi zofuzo eziphakeme ezihilelekile ezindleleni ze-lipogenesis, ukwanda kwe-ROS isizukulwane nokukhululwa kwe-Cytc kwabonwa enzalweni evezwe yi-BPA.Khona-ke, ukunqwabelana kwamafutha amaningi esibindini kanye neserum ephakeme ye-ALT kwabonwa enzalweni evezwe yi-BPA emavikini angama-26.Ekubukeni kwe-longitudinal, umsebenzi we-hepatic mitochondrial ohlanganisa umsebenzi we-MRC, ukukhiqizwa kwe-ATP, isizukulwane se-ROS kanye namandla e-membrane ye-mitochondrial kwaba kubi kancane kancane enzalweni evezwe yi-BPA.Ukuchayeka kwe-Perinatal BPA kunomthelela ekwakhiweni kwe-hepatic steatosis enzalweni yamagundane, okungahle kulamule ngokungasebenzi kahle kwe-hepatic mitochondrial kanye ne-up-regulated hepatic lipid metabolism.
