Imikhiqizo

Ukusetshenziswa kwe-silica capillary ehlanganisiwe ku-CE ngezinye izikhathi kungase kuphazamise ngenxa yemiphumela engathandeki ehlanganisa ukukhangisa kwesampula noma ukungazinzi kwe-EOF.Lokhu ngokuvamile kungagwenywa ngokumboza indawo engaphakathi ye-capillary.Kulo msebenzi, sethula futhi siveze amanoveli amabili e-polyelectrolyte coatings (PECs) poly(2-(methacryloyloxy)ethyl trimethylammonium iodide) (PMOTAI) kanye ne-poly(3-methyl-1-(4-vinylbenzyl)-imidazolium chloride) (PIL- 1) ngo-CE.Ama-capillaries amboziwe ahlolisiswa kusetshenziswa uchungechunge lwamabhafa anamanzi ane-pH ehlukahlukene, amandla e-ionic, kanye nokwakheka.Imiphumela yethu ibonisa ukuthi ama-polyelectrolyte aphenyiwe angasetshenziswa njengezingubo ezihlala njalo (ezikhangisiwe ngokomzimba) ezinokuzinza okungenani kwama-run amahlanu ngaphambi kokuthi kudingeke ukuvuselelwa okufushane kwe-coating.Womabili ama-PEC abonise ukuzinza okwehle kakhulu ku-pH 11.0.I-EOF ibiphezulu kusetshenziswa izibhafa ze-Good kune-sodium phosphate buffer ku-pH efanayo namandla e-ionic.Ubukhulu bezendlalelo ze-PEC ezifundwe i-quartz cry stal microbalance babungu-0.83 no-0.52 nm we-PMOTAI ne-PIL-1, ngokulandelanayo.I-hydrophobicity yezendlalelo ze-PEC yanqunywa ngokuhlaziywa kochungechunge lwe-alkyl benzoates oluyi-homologous futhi lwavezwa njengama-constants okusabalalisa.Umphumela wethu ubonisa ukuthi kokubili ama-PEC ayenayo i-hydrophobicity eqhathaniswayo, eyenza ukuhlukaniswa kwamakhompiyutha nge-log Po / w > 2. Ikhono lokuhlukanisa izidakamizwa ze-cationic liboniswe nge-β-blockers, izinhlanganisela ezivame ukusetshenziswa kabi ku-doping.Zombili izimbotshana zikwazile futhi ukuhlukanisa imikhiqizo ye-hydrolysis ye-ionic liquid 1,5-diazabicyclo [4.3.0] non-5-ene acetate ezimweni ezine-acidic kakhulu, lapho ama-silica capillaries angenalutho ahluleka ukufeza ukuhlukana.