Imikhiqizo

I-Ethyl 3-amino-4,4,4-trifluorocrotonate iyinhlanganisela ethola ukusetshenziswa ezindaweni ezihlukahlukene ezihlanganisa i-organic synthesis, chemistry medicinal, kanye nesayensi yezinto ezibonakalayo.Ukusetshenziswa okukhulu kwe-Ethyl 3-amino-4,4,4-trifluorocrotonate kunjengokuthi ibhlokhi yokwakha ku-organic synthesis.Iqukethe kokubili iqembu le-amine kanye nesibopho esiphindwe kabili, okwenza kube inkundla enemisebenzi eminingi yokwakha ama-molecule ayinkimbinkimbi.Iqembu le-amino lingenziwa lisebenze ngama-reagents ahlukahlukene ukwethula izinhlobonhlobo zokusebenza, kuyilapho isibopho esiphindwe kabili sivumela ukuguqulwa okwengeziwe kwesakhiwo.Le nhlanganisela ivame ukusetshenziswa ekuhlanganiseni kwemithi, ama-agrochemicals, nezinye izinhlanganisela eziphilayo ezisebenzayo.Ekhemistry yezokwelapha, i-Ethyl 3-amino-4,4,4-trifluorocrotonate ibonise amandla athembisayo njenge-scaffold yokuthuthukiswa kwemithi emisha.Iqembu le-trifluoromethyl laziwa ngokuthuthukisa amandla kanye nokuzinza kwe-metabolic yezidakamizwa, okwenza kube ukuguqulwa okukhangayo ekwakhiweni kwezidakamizwa.Le nhlanganisela isetshenziswe ekuhlanganiseni ama-inhibitors aqondise ama-enzyme ahlukahlukene nama-receptors, okuhlanganisa ama-kinases, ama-proteases, nama-receptors ahlanganiswe ne-G. Ngaphezu kwalokho, i-Ethyl 3-amino-4,4,4-trifluorocrotonate iphinde ithole ukusetshenziswa kwesayensi yezinto ezibonakalayo.Iqembu layo eliyingqayizivele le-trifluoromethyl linikeza izinto ezifiselekayo ezintweni eziwumphumela, njengokukhuphuka kwe-lipophilicity, ikhono elithuthukisiwe lokuhoxiswa kwe-electron, kanye nokupakishwa kwamangqamuzana okushintshiwe.Lokhu kwenza kube usizo ekuthuthukisweni kwezinto ezisebenzayo, ezifana nama-polymers, amakristalu e-liquid, nama-dyes.Ukwengeza, i-Ethyl 3-amino-4,4,4-trifluorocrotonate ingasetshenziswa njengesandulela ekuhlanganisweni kwezinhlanganisela ezihlukahlukene ze-fluorinated.Iqembu le-trifluoromethyl liyi-moiety ebalulekile kuma-molecule amaningi e-organic ngenxa yemiphumela ezuzisayo ku-physicochemical and biological properties.I-compound ingakwazi ukuguqulwa kwamakhemikhali ahlukahlukene, njenge-nucleophilic substitution, i-oxidation, nokunciphisa, ukunika amandla ukwethulwa noma ukuguqulwa kwamaqembu ane-fluorinated. ku-organic synthesis, i-chemistry yezokwelapha, nesayensi yezinto ezibonakalayo.Ikhono layo lokusebenza njengebhulokhi yokwakha, kanye neqembu layo eliyingqayizivele le-trifluoromethyl, kuyenza ibe yingxenye ebalulekile ekuthuthukisweni kwemithi ehlukahlukene, izinto zokwakha, kanye nezinhlanganisela ezine-fluorinated.