Imikhiqizo

I-Ethyl N- [3-amino-4-(methylamino)benzoyl]-N-pyridin-2-yl-beta-alaninate, evame ukubizwa nge-ethyl 3-amino-4-(methylamino)benzoate, iyinhlanganisela yamakhemikhali ne ifomula yamakhemikhali C15H19N3O2.Kuyinto esuselwe ngokwenziwa ethola ukusetshenziswa emikhakheni eyahlukene, okuhlanganisa ezemithi, ucwaningo, kanye ne-organic synthesis.Okunye ukusetshenziswa okuyinhloko kwe-ethyl N-[3-amino-4-(methylamino)benzoyl]-N-pyridin-2- I-yl-beta-alaninate isekuthuthukisweni kwemithi.Lesi sakhiwo sisebenza njengesakhiwo esibalulekile noma esiphakathi ekuhlanganiseni ama-ejenti ahlukahlukene emithi.Isakhiwo sayo esiyingqayizivele kanye nezakhiwo kuyenza ifanelekele ukuguqula kanye nokwenza kahle abantu abasebenzisa izidakamizwa.Abacwaningi bayisebenzisela ukwethula amaqembu athile asebenzayo noma izakhiwo zamangqamuzana ezingathuthukisa ukusebenza kahle kokwelapha, i-pharmacokinetics, noma i-bioavailability yama-molecule ezidakamizwa. Ngaphezu kwalokho, i-ethyl N-[3-amino-4-(methylamino)benzoyl]-N-pyridin-2- I-yl-beta-alaninate isetshenziswa ekuphenduleni kwe-organic synthesis.Ingabhekana noguquko oluhlukahlukene, njenge-acylation, i-amidation, kanye ne-esterification, ukuze yakhe inhlobonhlobo yemikhiqizo yamakhemikhali.Ukuphinda kusebenze kwayo kanye nokuguquguquka kwayo kuvumela osokhemisi ukuthi bethule amaqembu ahlukahlukene asebenzayo, baguqule izakhiwo zamakhemikhali, futhi bakhe ama-molecule ayinkimbinkimbi anezici ezithile ezizosetshenziswa embonini, ocwaningweni, noma ezifundweni.Ezikhungweni zokucwaninga, ososayensi bangasebenzisa i-ethyl N-[3-amino-4- (methylamino)benzoyl]-N-pyridin-2-yl-beta-alaninate njengenhlanganisela yereferensi noma i-reagent ngezinjongo zokuhlaziya.Ukuba khona kwayo ezixubeni zokusabela kungatholwa futhi kulinganiswe kusetshenziswa amasu okuhlaziya njenge-chromatography noma i-spectroscopy, okusiza ekuhlukaniseni abalingiswa nokuhlaziywa kwezingxube eziyinkimbinkimbi.Kubalulekile ukuphatha nokusebenzisa i-ethyl N-[3-amino-4-(methylamino) benzoyl ]-N-pyridin-2-yl-beta-alaninate ngokuqapha nangokuthobela izimiso zokuphepha.Lokhu kuhlanganisa ukugcinwa okufanele, ukuphatha, kanye nezinqubo zokulahla, njengoba kuyinhlanganisela yamakhemikhali engase ibangele izingozi uma ingaphathwa kahle noma isetshenziswe ngendlela engafanele.Hlala ubheka amashidi edatha yezokuphepha, landela iziqondiso ezimisiwe zokuphepha, futhi gqoka izinto zokuzivikela ezifanele uma usebenza nale nhlanganisela. I-beta-alaninate iyinhlanganisela eguquguqukayo esetshenziswa ekuthuthukisweni kwemithi, ukwakheka kwe-organic, kanye namakhemikhali okuhlaziya.Izici zayo zamakhemikhali eziyingqayizivele zivumela ukusetshenziswa kwayo njengesakhiwo sokwakhiwa kwezidakamizwa, ukuguqulwa kwezakhiwo zamakhemikhali, kanye nokuhlukaniswa kwezingxube eziyinkimbinkimbi.Kodwa-ke, izinyathelo ezifanele zokuphepha kufanele zilandelwe lapho kusetshenzwa nalesi sithako ukuze kuqinisekiswe ukuphathwa nokusetshenziswa okuphephile.