I-L-Cysteine hydrochloride anhydrous CAS:52-89-1 99% I-crystalline powder emhlophe
| Inombolo Yekhathalogi | XD90319 |
| Igama Lomkhiqizo | L-Cysteine hydrochloride anhydrous |
| I-CAS | 52-89-1 |
| I-Molecular Formula | C3H7NO2S·HCl |
| Isisindo samangqamuzana | 157.62 |
| Imininingwane Yesitoreji | 2 kuya ku-8 °C |
| Ikhodi Yentela Evumelanisiwe | 29309016 |
Ukucaciswa Komkhiqizo
| Ukubukeka | I-crystalline powder emhlophe |
| Isivivinyo | 99% |
| Ukuzungezisa okuqondile | +5.6 - +8.9 |
| Isiphetho | Ibanga le-AJI92 |
| Izinsimbi ezinzima | <10ppm |
| Ukuhlonza | I-spectrum yokumuncwa kwe-infrared |
| pH | 1.5 - 2 |
| Ukulahlekelwa Ekumisweni | <2.0% |
| Izinsalela ekushiseni | <0.1% |
| Amanye ama-amino acid | I-Chromatographically ayibonakali |
| I-Arsenic (as2O3) | <1ppm |
Isici esiyingozi esikhulu sokutheleleka kwe-Clostridium difficile (CDI) ukusetshenziswa kwemithi elwa namagciwane ngenxa yokuphazamiseka kokulingana kwe-host gut microbiota.Ukuze kugcinwe amagciwane anenzuzo ahlala e-probiotic ngesikhathi sokwelashwa kokutheleleka, ukusetshenziswa kwama-molecule anomsebenzi okhethekile we-antibacterial kuthuthukisa ukusebenza kahle ngokukhipha i-C. difficile ngokukhetha.Esinye sazo yisitshalo se-alkaloid 8-hydroxyquinoline (8HQ), esiye saboniswa ukuthi sinqande i-clostridia ngaphandle kokucindezela i-bifidobacteria.Umsebenzi okhethiwe wama-antimicrobial ngokuvamile uhlolwa ngamasu amasiko ezinhlobo zebhaktheriya ngalinye.Kodwa-ke, umkhawulo oyinhloko walezi zindlela ukungakwazi ukuchaza ukushintshashintsha kokukhula okuhlukile kwezinhlobo eziningi zebhaktheriya ku-co-culture ngaphakathi kokuhlolwa okufanayo.Ocwaningweni lwamanje, sihlanganise i-fluorescent in situ hybridization kanye ne-cytometry yokugeleza ukuze sichaze izinguquko kumaseli asebenzayo nangasebenzi wesiko elixubile elakhiwe yi-pathogen engosomathuba C. diff icile CECT 531 kanye ne-Bifidobacterium longum subsp enenzuzo.longum CCMDMND BL1 ngemva kokuchayeka ku-8HQ.Kwaphawulwa ukuthi ngaphandle kwe-8HQ, ingxenye yazo zombili izinhlobo yayicishe ilingane, inyakaza phakathi kuka-22.7 no-77.9 % ngesikhathi sokuphela kwesikhathi samahora angu-12, kanti nge-8HQ ingxenye ye-C. difficile esebenzayo yehla ngemva kwamahora angu-4, futhi iqhubeka phakathi kuka-8.8 kuphela. kanye no-17.5%.Ngokuphambene, ukukhula kwe-bifidobacterial akuzange kuphazanyiswe yi-8HQ.Imiphumela yalolu cwaningo ibonise umphumela okhethiwe we-inhibitory we-8HQ ku-clostridial kanye ne-bifidobacterial ukukhula dynamics, kanye namandla alesi sakhi sokuthuthukiswa kwama-agent akhethiwe ukulawula ama-CDI.
