(2S,3R) -2-Amino-3-hydroxybutanoic acid Cas: 72-19-5 99% Impushana emhlophe ecwebezelayo
| Inombolo Yekhathalogi | XD90285 |
| Igama Lomkhiqizo | (2S,3R) -2-Amino-3-hydroxybutanoic acid |
| I-CAS | 72-19-5 |
| I-Molecular Formula | C4H9NO3 |
| Isisindo samangqamuzana | 119.11916 |
| Imininingwane Yesitoreji | I-ambient |
| Ikhodi Yentela Evumelanisiwe | 29225000 |
Ukucaciswa Komkhiqizo
| Isivivinyo | 99 - 101% |
| Ukubukeka | I-crystalline powder emhlophe |
| Ukuzungezisa okuqondile | -27.5 ukuze -29.0 |
| Izinsimbi ezinzima | 10ppm Max. |
| AS | 10ppm ubuningi |
| pH | 5.2 - 6.5 |
| I-SO4 | <0.020% |
| Fe | 10ppm ubuningi |
| Ukulahlekelwa Ekumisweni | <0.20% |
| Izinsalela ekushiseni | <0.10% |
| Ukudlulisa | I-NLT 98% |
| Cl | <0.02% |
| Usawoti we-ammonium | <0.02% |
I-Serine/threonine protein phosphatases iye yachazwa kumagciwane amaningi e-pathogenic njengama-enzyme abalulekile ahilelekile emigwaqweni yokudlulisela isignali encike ku-phosphorylation futhi evame ukuhlotshaniswa ne-virulence yalezi zinambuzane.Ukuhlolwa kwe-Mycoplasma synoviae genome kwembula ukuba khona kofuzo (prpC) olufaka i-puative protein phosphatase ye-protein phosphatase 2C (PP2C) subfamily.Lapha, sibika ukucaciswa okuphelele kwe-biochemical ye-M. synoviae phosphatase (PrpC) kanye nendima ethile yama-ion ensimbi ebudlelwaneni bomsebenzi wesakhiwo wale enzyme.Ukuhlaziywa kokulandelana kwe-amino acid ye-PrpC kwembule ukuthi zonke izinsalela ezihilelekile esikhungweni sensimbi ye-dinuclear kanye nezinsalela ze-ion-coordinating zensimbi yesithathu, ezilondolozwe kuma-phosphatase e-PP2C, zikhona ku-PrpC.I-PrpC iyiphrotheni ye-monomeric ekwazi ukukhipha i-phospho-substrates ngokuncika kwe-Mn(2+) ions'.Ukuhlaziywa kokuzinza kokushisa kubonise ukuzinza kwe-enzyme emazingeni okushisa aphansi kanye nomthelela wama-ion angu-Mn(2+) kulesi sakhiwo.Ukuhlaziywa kwe-mass spectrometry kuphakamise ukuthi ama-ion ensimbi amathathu abophezele ku-PrpC, amabili awo anokuqina okuhambisanayo okuphezulu.Ukuhlaziya okuguquguqukayo kwezinsalela zokuxhumanisa insimbi yesithathu, i-Asp122 kanye ne-Arg164, kwembula ukuthi lezi zinhlobonhlobo zibonisa ukubophezela okubuthakathaka kwama-ion we-manganese, nokuthi kokubili ukuguqulwa kuthinte umsebenzi we-PrpC phosphatase.Ngokwale miphumela, i-PrpC iyilungu le-protein phosphatase elincike ensimbi elinozinzo oluthuthukisiwe kufomu le-holo kanye ne-Asp122, okungenzeka ukuthi ifakwe endaweni yesithathu yokubopha insimbi, ebalulekile kumsebenzi wokuvuselela amandla.
