I-Glutathione inciphise i-Cas: 70-18-8 98-101% Icacile futhi ayinambala
| Inombolo Yekhathalogi | XD90284 |
| Igama Lomkhiqizo | I-Glutathione iyancipha |
| I-CAS | 70-18-8 |
| I-Molecular Formula | I-C10H17N3O6S |
| Isisindo samangqamuzana | 307.32 |
| Imininingwane Yesitoreji | 2 kuya ku-8 °C |
| Ikhodi Yentela Evumelanisiwe | 29309098 |
Ukucaciswa Komkhiqizo
| Isivivinyo | 98% - 101% |
| Ukubukeka | I-crystalline powder emhlophe |
| Ibanga | EP 7.0 |
| Ukungcola A | <0.5% |
| Ukungcola B | <0.5% |
| Izinsimbi ezinzima | <10ppm |
| I-endotoxin yebhaktheriya | <0.10EU/mg |
| Ukungcola C | <1.5% |
| Ukungcola D | <1.0% |
| Ukulahlekelwa Ekumisweni | <0.5% |
| Ukuncibilika | Incibilika ngokukhululekile emanzini, incibilika kancane ku-ethanol ne-methylene chloride |
| Insimbi | <10ppm |
| Ama-Chloride | <200ppm |
| Ukubukeka Kwesixazululo | Icacile futhi ayinambala |
| Ukujikeleza okuqondile okubonakalayo | -15.5 kuya ku-17.5 |
| Ukungcola Okuphelele | <2.5% |
| I-ammonium | <200ppm |
| Umlotha one-sulfate | <0.1% |
| Ama-sulphate | <300ppm |
| Ukungcola E | <0.5% |
Ukuguqulwa kwamaprotheni ngemva kokuhumusha, njenge-tyrosine phosphorylation, kulawula ukusebenzisana kwamaprotheni-protein (PPIs) okubalulekile ekucubunguleni isignali nama-phenotypes eselula.Sandise uhlelo olusunguliwe lwe-yeast two-hybrid esebenzisa amaprotheni kinases womuntu ukuze kuhlaziywe ama-PPI ancike ku-phospho-tyrosine (pY) ngendlela yokuhlola eqondile, nesilinganiso esikhulu.Sihlonze ama-PPI angu-292 ikakhulukazi amanoveli ancike ku-pY abonise ukucaciswa okuphezulu maqondana nama-kinases namaprotheni asebenzisanayo futhi saqinisekisa ingxenye enkulu ekuhlolweni kwe-co-immunoprecipitation kusuka kumaseli ezincelisayo.Cishe ingxenye eyodwa kwesithupha yokusebenzelana iqondiswa ama-motif abophezelayo alandelanayo alandelanayo kuyilapho iningi lama-pY-PPI lilamula amanye ama-epitopes anomugqa noma kubuswa ezinye izindlela zokuqaphela.Ukuhlaziywa kwenethiwekhi kwembula ukuthi imicimbi yokuqashelwa kwe-pY-mediated iboshelwe kumojula yephrotheni exhumeke kakhulu enikezelwe ekuboniseni nasekukhuleni kweseli ezindleleni ezihlobene nomdlavuza.Sisebenzisa izivivinyo ezibophayo, i-protein complement ntation kanye nokufundwa kwe-phenotypic ukuze kubonise ukusebenzisana okuncike ku-pY kwe-TSPAN2 (tetraspanin 2) kanye ne-GRB2 noma i-PIK3R3 (p55γ), sinika isibonelo sokuthi ama-PPI amabili ancike ku-pY asho ama-phenotypes omdlavuza weselula.
