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Imikhiqizo

I-Glutathione oxidized Cas: 27025-41-8 White crystalline powder

Incazelo emfushane:

Inombolo Yekhathalogi: XD90283
I-Cas: 27025-41-8
I-Molecular Formula: I-C20H32N6O12S2
Isisindo se-Molecular: 612.63
Ukutholakala: Kukhona kusitoki
Inani:  
I-Prepack: 5g USD20
Iphakethe lenqwaba: Cela i-Quote

 

 

 

 

 


Imininingwane Yomkhiqizo

Omaka bomkhiqizo

Inombolo Yekhathalogi XD90283
Igama Lomkhiqizo I-Glutathione i-oxidized

I-CAS

27025-41-8

I-Molecular Formula

I-C20H32N6O12S2

Isisindo samangqamuzana

612.63
Imininingwane Yesitoreji 2 kuya ku-8 °C

Ikhodi Yentela Evumelanisiwe

2930909899

 

Ukucaciswa Komkhiqizo

Isivivinyo 99%
Ukubukeka I-crystalline powder emhlophe
Ukuzungezisa okuqondile -96 kuya ku-106
Izinsimbi ezinzima 10ppm ubuningi
AS 2ppm ubuningi
Ukulahlekelwa Ekumisweni 15.0% ubuningi.
Ubumsulwa 95% min
Izinsalela ekushiseni 0.5% ubuningi

I-Hepatotoxicity yabaqokelwe izidakamizwa ingenye yezinto ezikhathazayo ezinkulu ekuhlolweni kwezidakamizwa ekutholweni kwezidakamizwa kusenesikhathi.Ukutholwa kokucindezeleka kwe-hepatic oxidative kungaba inkomba yokuqala ye-hepatotoxicity futhi kuzuzise ukukhethwa kwezidakamizwa.I-glutathione (GSH) kanye ne-glutathione disulfide (GSSG) pair, njengenye ye-intracellular redox elawula imibhangqwana, idlala indima ebalulekile ekuvikeleni amangqamuzana ekucindezelekeni kwe-oxidative okubangelwa ukungalingani phakathi kwama-prooxidants nama-antioxidants.Ukunqunywa komthamo wezilinganiso ze-GSSG/GSH kanye nokugxila kwe-GSH ne-GSSG kusetshenziswe ukukhombisa ukucindezeleka kwe-oxidative kumaseli namathishu.Kulolu cwaningo, sihlole ukuthi kungenzeka yini ukusebenzisa izilinganiso ze-GSSG/GSH ze-biliary njenge-biomarker ukukhombisa ingcindezi ye-hepatic oxidative kanye nobuthi bezidakamizwa.Izinhlanganisela ezine ezaziwa ngokushintsha amazinga e-GSH kanye ne-GSSG zihloliwe kulolu cwaningo.I-Diquat (i-diquat dibromide monohydrate) ne-acetaminophen yanikezwa amagundane.I-Paraquat ne-tert-butyl hydroperoxide yanikezwa d kumagundane ukuze yenze izinguquko ze-GSH ye-biliary ne-GSSG.I-GSH ne-GSSG ye-biliary ziye zalinganiswa kusetshenziswa amajika okulinganisa alungiselelwe nge-bile yokwenziwa ukuze kulandiswe nganoma yimuphi umphumela we-bile matrix ekuhlaziyweni kwe-LC-MS kanye nokugwema ukugxambukela kwe-GSH engapheli kanye ne-GSSG.Ngezibonelo ezine (kumagundane namagundane) zezinguquko ezibangelwa izidakamizwa ku-kinetics yezilinganiso ze-biliary GSSG/GSH, lolu cwaningo lubonise amandla okuthuthukisa inkomba yempendulo yokuchayeka esekelwe kuzilinganiso ze-GSSG/GSH ze-biliary zokubikezela ukucindezeleka kwe-hepatic oxidative.


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    I-Glutathione oxidized Cas: 27025-41-8 White crystalline powder