I-L-Histidine Cas: 71-00-1 98.5% Amakristalu amhlophe noma i-crystalline powder
| Inombolo Yekhathalogi | I-XD90301 |
| Igama Lomkhiqizo | I-L-Histidine |
| I-CAS | 71-00-1 |
| I-Molecular Formula | I-C6H9N3O2 |
| Isisindo samangqamuzana | 155.15 |
| Imininingwane Yesitoreji | I-ambient |
| Ikhodi Yentela Evumelanisiwe | 29332990 |
Ukucaciswa Komkhiqizo
| Isivivinyo | 98.5% iminithi |
| Ukubukeka | Amakristalu amhlophe noma i-crystalline powder |
| Ibanga | I-USP39 |
| Ukuzungezisa okuqondile | +12.6 ° ukuze +14.0 ° |
| Ukuhlonza | Ukumuncwa kwe-infrared |
| pH | 7.0 - 8.5 |
| I-SO4 | <=0.03% |
| Fe | <=30ppm |
| Ukulahlekelwa Ekumisweni | <=0.2% |
| Izinsalela ekushiseni | <=0.1% |
| Cl | <=0.05% |
| Izinsimbi ezinzima (PB) | <=15ppm |
| Izinhlanganisela ezihlobene | Akukho ngaphezu kwe-0.5% yanoma yikuphi ukungcola komuntu ngamunye okutholakalayo;Akutholakali ngaphezu kuka-2.0% wokungcola okuphelele |
I-he quadruplex eyenza ukulandelana kwe-G-rich asatshalaliswa ngokungalingani kulo lonke i-genome yomuntu.Ukucebisa kwabo kubagqugquzeli be-oncogenic nama-telomere kukhiqize intshisekelo yokukhomba i-G-quadruplex (GQ) yokwelapha okulwa nomdlavuza.Lapha, sethula ukuhlaziya kobuningi bokuvumelana kanye namandla okulandelana okwakhiwa kwe-GQ okukalwa nge-fluorescence ye-molecule eyodwa.Ukwengeza, sihlobanisa lezi zakhiwo nama-GQ aqondise ama-ligand kanye ne-G4 resolvase 1 (G4R1) yokubophezela kwamaprotheni.Umphumela wethu ubonisa ukuthi kokubili iluphu (izingxenye ezingezona eze-G) ubude nokulandelana kunomthelela ekwakhiweni kwe-GQ.Ukulandelela kwe-molecule yesikhathi sangempela kuveza ukuthi amandla okugoqa nawo ancike ekwakhiweni kweluphu.Sibonisa ukuthi i-GQ-izinzisa ama-molecule amancane, i-N-methyl mesoporphyrin IX (NMM), i-analog yayo, i-NMP kanye nephrotheni ye-G4R1 abopha ngokukhetha ukuhambisana kwe-GQ okuhambisanayo.Okutholakele kwethu kukhomba inkimbinkimbi yokugoqa kwe-GQ okubuswa ubude beluphu nokulandelana nokuthi ukuhambisana kwe-GQ kunquma kanjani i-molecule encane kanye nokuthambekela kokubopha amaprotheni.
